Descriptor English: | Uncoupling Agents | ||||||
Descriptor Spanish: |
Desacopladores
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Descriptor Portuguese: | Desacopladores | ||||||
Descriptor French: | Agents découplants | ||||||
Entry term(s): |
Agents, Uncoupling |
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Tree number(s): |
D27.505.519.389.936 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D014475 | ||||||
Scope note: | Chemical agents that uncouple oxidation from phosphorylation in the metabolic cycle so that ATP synthesis does not occur. Included here are those IONOPHORES that disrupt electron transfer by short-circuiting the proton gradient across mitochondrial membranes. |
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Annotation: | enzyme inhib |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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Previous Indexing: |
Oxidative Phosphorylation/drug effects (1966-1968) Oxidoreductases/antagonists & inhibitors (1968) |
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Public MeSH Note: | 72; DIO-9 was see under ANTIBIOTICS 1975-81 |
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History Note: | 72(69) |
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Related: |
Ionophores
MeSH | ||||||
DeCS ID: | 14874 | ||||||
Unique ID: | D014475 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1972/01/01 | ||||||
Date of Entry: | 1999/01/01 | ||||||
Revision Date: | 2014/06/25 |
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CHEMICALS AND DRUGS
Chemical Actions and Uses [D27]Chemical Actions and Uses
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Uncoupling Agents
- Preferred
Concept UI |
M0022252 |
Scope note | Chemical agents that uncouple oxidation from phosphorylation in the metabolic cycle so that ATP synthesis does not occur. Included here are those IONOPHORES that disrupt electron transfer by short-circuiting the proton gradient across mitochondrial membranes. |
Preferred term | Uncoupling Agents |
Entry term(s) |
Agents, Uncoupling |
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