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Descriptor English: Histone Deacetylase Inhibitors
Descriptor Spanish: Inhibidores de Histona Desacetilasas
Descriptor inhibidores de histona desacetilasas
Entry term(s) inhibidor de HDAC
inhibidores de las desacetilasas de histonas
Scope note: Compuestos que inhiben las HISTONAS DESACETILASAS. Esta clase de fármacos puede influir en la expresión génica al aumentar la concentración de HISTONAS acetiladas en dominios de CROMATINA específicos.
Descriptor Portuguese: Inibidores de Histona Desacetilases
Descriptor French: Inhibiteurs de désacétylase d'histone
Entry term(s): Deacetylase Inhibitor, Histone
Deacetylase Inhibitors, Histone
HDAC Inhibitor
HDAC Inhibitors
Histone Deacetylase Inhibitor
Inhibitor, HDAC
Inhibitor, Histone Deacetylase
Inhibitors, HDAC
Inhibitors, Histone Deacetylase
Tree number(s): D27.505.519.389.360
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D056572
Scope note: Compounds that inhibit HISTONE DEACETYLASES. This class of drugs may influence gene expression by increasing the level of acetylated HISTONES in specific CHROMATIN domains.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Histone Deacetylases/antagonists & inhibitors (1978-2009)
Public MeSH Note: 2010
History Note: 2010
DeCS ID: 53667
Unique ID: D056572
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2020/05/27
Histone Deacetylase Inhibitors - Preferred
Concept UI M0527853
Scope note Compounds that inhibit HISTONE DEACETYLASES. This class of drugs may influence gene expression by increasing the level of acetylated HISTONES in specific CHROMATIN domains.
Preferred term Histone Deacetylase Inhibitors
Entry term(s) Deacetylase Inhibitor, Histone
Deacetylase Inhibitors, Histone
HDAC Inhibitor
HDAC Inhibitors
Histone Deacetylase Inhibitor
Inhibitor, HDAC
Inhibitor, Histone Deacetylase
Inhibitors, HDAC
Inhibitors, Histone Deacetylase



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