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Descriptor English: Neurotensin
Descriptor Spanish: Neurotensina
Descriptor neurotensina
Scope note: Tridecapéptido biológicamente activo aislado del hipotálamo. Se ha demostrado que induce hipotensión en la rata, que estimula la contracción del íleo en el cobaya y del útero en la rata y que produce relajación del duodeno en la rata. Hay también datos de que actúa como neurotransmisor en el sistema nervioso periférico y central.
Descriptor Portuguese: Neurotensina
Descriptor French: Neurotensine
Tree number(s): D12.644.400.550
D12.776.631.650.550
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009496
Scope note: A biologically active tridecapeptide isolated from the hypothalamus. It has been shown to induce hypotension in the rat, to stimulate contraction of guinea pig ileum and rat uterus, and to cause relaxation of rat duodenum. There is also evidence that it acts as both a peripheral and a central nervous system neurotransmitter.
Annotation: a neurotransmitter isolated from the hypothalamus; /biosyn /physiol permitted
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 39379-15-2
CAS Type 1 Name: Neurotensin
Previous Indexing: Kinins (1966-1977)
Nerve Tissue Proteins (1966-1977)
Peptides (1966-1977)
Public MeSH Note: 78
History Note: 78
Related: Receptors, Neurotensin MeSH
DeCS ID: 22580
Unique ID: D009496
NLM Classification: WL 104
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1978/01/01
Date of Entry: 1977/05/23
Revision Date: 2015/11/24
Neurotensin - Preferred
Concept UI M0014773
Scope note A biologically active tridecapeptide isolated from the hypothalamus. It has been shown to induce hypotension in the rat, to stimulate contraction of guinea pig ileum and rat uterus, and to cause relaxation of rat duodenum. There is also evidence that it acts as both a peripheral and a central nervous system neurotransmitter.
Preferred term Neurotensin



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