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Descriptor English: Monensin
Descriptor Spanish: Monensina
Descriptor monensina
Scope note: Agente antiprotozoario producido por el Streptomyces cinnamonensis. Ejerce sus efectos durante el desarrollo de tropozoitos de primera generación a esquizontes de primera generación, en el interior de la células epiteliales intestinales. Para la mayoría de las especies de coccidios no interfiere en el desarrollo de la inmunidad adquirida por el huesped. La monensina es un ionóforo selectivo de sodio y protones, por lo que se utiliza mucho en estudios bioquímicos.
Descriptor Portuguese: Monensin
Descriptor French: Monensin
Entry term(s): Coban
Monensin A Sodium Complex
Monensin Monosodium Salt
Monensin Sodium
Monensin-A-Sodium Complex
Rumensin
Tree number(s): D02.355.291.933.500
D02.540.576.625.500
D03.383.312.600
D04.345.241.654.500
D04.345.674.625.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008985
Scope note: An antiprotozoal agent produced by Streptomyces cinnamonensis. It exerts its effect during the development of first-generation trophozoites into first-generation schizonts within the intestinal epithelial cells. It does not interfere with hosts' development of acquired immunity to the majority of coccidial species. Monensin is a sodium and proton selective ionophore and is widely used as such in biochemical studies.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antifungal Agents
Antiprotozoal Agents
Coccidiostats
Proton Ionophores
Sodium Ionophores
Registry Number: 906O0YJ6ZP
CAS Type 1 Name: Monensin
Previous Indexing: Antibiotics (1972-1974)
Furans (1974)
Pyrans (1974)
Public MeSH Note: 87; was see under FURANS 1975-86
History Note: 87(75); was see under FURANS 1975-86
DeCS ID: 23319
Unique ID: D008985
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1987/01/01
Date of Entry: 1974/11/19
Revision Date: 2016/05/31
Monensin - Preferred
Concept UI M0014007
Scope note An antiprotozoal agent produced by Streptomyces cinnamonensis. It exerts its effect during the development of first-generation trophozoites into first-generation schizonts within the intestinal epithelial cells. It does not interfere with hosts' development of acquired immunity to the majority of coccidial species. Monensin is a sodium and proton selective ionophore and is widely used as such in biochemical studies.
Preferred term Monensin
Rumensin - Narrower
Concept UI M0014008
Preferred term Rumensin
Coban - Narrower
Concept UI M0353181
Preferred term Coban
Monensin Sodium - Narrower
Concept UI M0330043
Preferred term Monensin Sodium
Entry term(s) Monensin A Sodium Complex
Monensin Monosodium Salt
Monensin-A-Sodium Complex



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