DeCS

Descriptor English:

Deoxyribonucleases, Type II Site-Specific

Descriptor Spanish:

Desoxirribonucleasas de Localización Especificada Tipo II

Spanish from Spain

Descriptor	desoxirribonucleasas específicas del sitio de tipo II
Entry term(s)	DNasa específica del sitio de tipo II desoxirribonucleasas sitio-específicas tipo II endocnucleasas de restricción de tipo II enzimas de restricción de tipo II enzimas de restricción del ADN de tipo II
Scope note:	Sistemas enzimáticos que contienen una sola subunidad y requieren exclusivamente magnesio para su actividad endonucleolítica. Las correspondientes metilasas de modificación son enzimas separadas. Los sistemas reconocen secuencias específicas cortas del ADN y escinden en sitios que están en la secuencia de reconocimiento o cerca de ella, produciendo fragmentos bicatenarios específicos con 5'-fostafos terminales. Las enzimas de diferentes microorganismos con la misma especificidad se denominan isoesquizómeros. EC 3.1.21.4.

Descriptor Portuguese:

Desoxirribonucleases de Sítio Específico do Tipo II

Descriptor French:

Type II site-specific deoxyribonuclease

Entry term(s):

DNA Restriction Enzymes, Type II
DNase, Site Specific, Type II
DNase, Site-Specific, Type II
Deoxyribonucleases, Type II Site Specific
Deoxyribonucleases, Type II, Site Specific
Deoxyribonucleases, Type II, Site-Specific
Restriction Endonucleases, Type II
Site Specific DNase, Type II
Site-Specific DNase, Type II
Type II Restriction Enzymes
Type II Site Specific DNase
Type II Site Specific Deoxyribonucleases
Type II Site-Specific DNase
Type II Site-Specific Deoxyribonucleases

Tree number(s):

D08.811.150.280.260
D08.811.277.352.335.350.300.260
D08.811.277.352.355.325.300.260

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D015252

Scope note:

Enzyme systems containing a single subunit and requiring only magnesium for endonucleolytic activity. The corresponding modification methylases are separate enzymes. The systems recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 3.1.21.4.

Allowable Qualifiers:

AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine

Concept UI	M0023490
Scope note	Enzyme systems containing a single subunit and requiring only magnesium for endonucleolytic activity. The corresponding modification methylases are separate enzymes. The systems recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 3.1.21.4.
Preferred term	Deoxyribonucleases, Type II Site-Specific
Entry term(s)	DNA Restriction Enzymes, Type II DNase, Site Specific, Type II DNase, Site-Specific, Type II Deoxyribonucleases, Type II Site Specific Deoxyribonucleases, Type II, Site Specific Deoxyribonucleases, Type II, Site-Specific Restriction Endonucleases, Type II Site Specific DNase, Type II Site-Specific DNase, Type II Type II Restriction Enzymes Type II Site Specific DNase Type II Site Specific Deoxyribonucleases Type II Site-Specific DNase Type II Site-Specific Deoxyribonucleases

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