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Descriptor in English: Serotonin
Descriptor in Spanish: Serotonina
Descriptor in Portuguese: Serotonina
Descriptor in French: Sérotonine
Entry term(s): 3-(2-Aminoethyl)-1H-indol-5-ol
5 Hydroxytryptamine
5-HT
5-Hydroxytryptamine
Enteramine
Hippophaine
Hydroxytryptamine
Tree number(s): D02.092.211.215.801.852
D03.633.100.473.914.814
D23.469.050.650
Scope note: A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
Annotation: /antag = SEROTONIN ANTAGONISTS but consider also SEROTONIN UPTAKE INHIBITORS
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Online Note: use SEROTONIN to search HYDROXYTRYPTAMINE 1975-92
History Note: HYDROXYTRYPTAMINE was see SEROTONIN 1975-92
See also the descriptors: Receptors, Serotonin MeSH
Serotonin Agents MeSH
Serotonin Syndrome MeSH
DeCS UI: 24311
Descriptor UI: D012701
Date Established: 1960/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Serotonin - Preferred
Concept UI M0019683
Scope note A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
Preferred term Serotonin
Entry term(s) 3-(2-Aminoethyl)-1H-indol-5-ol
5 Hydroxytryptamine
5-HT
5-Hydroxytryptamine
Enteramine
Hippophaine
Hydroxytryptamine - Related but not broader or narrower
Concept UI M0019684
Preferred term Hydroxytryptamine



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