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Descriptor English: Platelet Activating Factor
Descriptor Spanish: Factor de Activación Plaquetaria
Descriptor Portuguese: Fator de Ativação de Plaquetas
Descriptor French: Facteur d'activation plaquettaire
Entry term(s): 1 Alkyl 2 acetyl sn glycerophosphocholine
1-Alkyl-2-acetyl-sn-glycerophosphocholine
AGEPC
Acetyl Glyceryl Ether Phosphorylcholine
Aggregating Factor, Platelet
Factor, Platelet Activating
PAF Acether
PAF-Acether
Phosphorylcholine, Acetyl Glyceryl Ether
Platelet Activating Substance
Platelet Aggregating Factor
Platelet Aggregation Enhancing Factor
Platelet-Activating Substance
Thrombocyte Aggregating Activity
Tree number(s): D02.033.100.291.211.500
D02.092.063.291.211.500
D02.092.877.883.333.710
D02.675.276.232.710
D10.570.755.375.760.400.985.910
D23.119.865
D23.469.050.600
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010972
Scope note: A phospholipid derivative formed by PLATELETS; BASOPHILS; NEUTROPHILS; MONOCYTES; and MACROPHAGES. It is a potent platelet aggregating agent and inducer of systemic anaphylactic symptoms, including HYPOTENSION; THROMBOCYTOPENIA; NEUTROPENIA; and BRONCHOCONSTRICTION.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Lysophosphatidylcholines (1966-1980)
Public MeSH Note: 1983; PLATELET AGGREGATING FACTOR was indexed under PLATLET ACTIVATING FACTOR 2002-2005 & BLOOD COAGULATION FACTORS 1979-2001
History Note: 1983(1979)
DeCS ID: 23518
Unique ID: D010972
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1983/01/01
Date of Entry: 1982/05/11
Revision Date: 2005/06/30
Platelet Activating Factor - Preferred
Concept UI M0017009
Scope note A phospholipid derivative formed by PLATELETS; BASOPHILS; NEUTROPHILS; MONOCYTES; and MACROPHAGES. It is a potent platelet aggregating agent and inducer of systemic anaphylactic symptoms, including HYPOTENSION; THROMBOCYTOPENIA; NEUTROPENIA; and BRONCHOCONSTRICTION.
Preferred term Platelet Activating Factor
Entry term(s) 1 Alkyl 2 acetyl sn glycerophosphocholine
1-Alkyl-2-acetyl-sn-glycerophosphocholine
AGEPC
Acetyl Glyceryl Ether Phosphorylcholine
Aggregating Factor, Platelet
Factor, Platelet Activating
PAF Acether
PAF-Acether
Phosphorylcholine, Acetyl Glyceryl Ether
Platelet Activating Substance
Platelet Aggregating Factor
Platelet Aggregation Enhancing Factor
Platelet-Activating Substance
Thrombocyte Aggregating Activity



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