| Descriptor English: | Histamine | ||||
| Descriptor Spanish: | 
                                Histamina                                        
                                        
                                                                                                                            
                                            
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| Descriptor Portuguese: | Histamina | ||||
| Descriptor French: | Histamine | ||||
| Entry term(s): | 
                                    Ceplene Histamine Dihydrochloride Histamine Hydrochloride Peremin  | 
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| Tree number(s): | 
                                        D02.092.211.215.501 D02.092.471.440 D03.383.129.308.373 D23.469.050.300  | 
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D006632 | ||||
| Scope note: | An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. | 
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| Allowable Qualifiers: | 
                                                                        AA                                                            analogs & derivatives AD administration & dosage AE adverse effects AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine  | 
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| Entry Combination: | 
                                                                            antagonists & inhibitors:Histamine Antagonists
                                                                                 agonists:Histamine Agonists  | 
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| Pharm Action: | 
                                                                                                    Histamine Agonists | 
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| Registry Number: | 820484N8I3 | ||||
| CAS Type 1 Name: | 1H-Imidazole-4-ethanamine | ||||
| Public MeSH Note: | /antagonists & inhibitors was ANTIHISTAMINICS 1963-76 | 
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| Online Note: | search HISTAMINE /antagonists & inhibitors under HISTAMINE H1 RECEPTOR BLOCKADERS 1966-76 | 
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| History Note: | /antagonists & inhibitors was ANTIHISTAMINICS 1963-76 | 
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| Related: | 
                                                                                                                        Histamine Release
                                            MeSH                                             Hypersensitivity, Immediate MeSH Receptors, Histamine MeSH  | ||||
| DeCS ID: | 24208 | ||||
| Unique ID: | D006632 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 1960/01/01 | ||||
| Date of Entry: | 1999/01/01 | ||||
| Revision Date: | 2018/06/13 | 
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                                        CHEMICALS AND DRUGS
 
Organic Chemicals [D02]Organic Chemicals - 
                                    
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals - 
                                    
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds - 
                                    
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors 
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                        Histamine                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                                                                    
                        Peremin                                            
                                        - Related but not broader or narrower                                        
                                                                
                                
                                                                    
                        Histamine Dihydrochloride                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Histamine Hydrochloride                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Ceplene                                            
                                        - Narrower                                        
                                                                
                                
                        
                        
                    
                    
                
                | Concept UI | 
                                        
                                        M0010390 | 
                                
| Scope note | An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. | 
| Preferred term | Histamine | 
| Concept UI | 
                                        
                                        M0010391 | 
                                
| Preferred term | Peremin | 
| Concept UI | 
                                        
                                        M0010392 | 
                                
| Preferred term | Histamine Dihydrochloride | 
| Concept UI | 
                                        
                                        M000638464 | 
                                
| Preferred term | Histamine Hydrochloride | 
| Concept UI | 
                                        
                                        M0455955 | 
                                
| Scope note | Tradename for histamine dihydrochloride. | 
| Preferred term | Ceplene | 
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