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Descriptor English: Cathepsin A
Descriptor Spanish: Catepsina A
Descriptor catepsina A
Entry term(s) carboxipeptidasa C
carboxipeptidasa Y
proteína protectora de los lisosomas
proteína protectora lisosómica
Scope note: Una carboxipeptidase que cataliza la liberación de un aminoácido C-terminal con una amplia especificidad. También desempeña una función en los LISOSOMAS, protegiendo de la degradación a la BETA-GALACTOSIDASA y a la NEURAMINIDASA. Fue clasificada antiguamente como EC 3.4.12.1 y EC 3.4.21.13.
Descriptor Portuguese: Catepsina A
Descriptor French: Cathepsine A
Entry term(s): Acid Carboxypeptidase
BGPP
Carboxypeptidase C
Carboxypeptidase Y
Endothelin Degradation Enzyme
Lysosomal Protective Protein
Serine Carboxypeptidase I
beta Galactosidase Protective Protein
beta-Galactosidase Protective Protein
Tree number(s): D08.811.277.656.224.062
D08.811.277.656.350.245.260
D08.811.277.656.959.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D043402
Scope note: A carboxypeptidase that catalyzes the release of a C-terminal amino acid with a broad specificity. It also plays a role in the LYSOSOMES by protecting BETA-GALACTOSIDASE and NEURAMINIDASE from degradation. It was formerly classified as EC 3.4.12.1 and EC 3.4.21.13.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.4.16.5
Previous Indexing: Carboxypeptidases (1968-2003)
Cathepsins (1965-2003)
Public MeSH Note: 2010; for CATHEPSIN A see CARBOXYPEPTIDASE C 2004-2009; CATHEPSIN A was indexed under CARBOXYPEPTIDASES 1995-2003
History Note: 2010(1995)
DeCS ID: 38167
Unique ID: D043402
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2009/07/06
Cathepsin A - Preferred
Concept UI M0242181
Scope note A carboxypeptidase that catalyzes the release of a C-terminal amino acid with a broad specificity. It also plays a role in the LYSOSOMES by protecting BETA-GALACTOSIDASE and NEURAMINIDASE from degradation. It was formerly classified as EC 3.4.12.1 and EC 3.4.21.13.
Preferred term Cathepsin A
Entry term(s) Acid Carboxypeptidase
BGPP
Carboxypeptidase C
Carboxypeptidase Y
Endothelin Degradation Enzyme
Lysosomal Protective Protein
Serine Carboxypeptidase I
beta Galactosidase Protective Protein
beta-Galactosidase Protective Protein



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