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Descriptor English: Cathepsin D
Descriptor Spanish: Catepsina D
Descriptor catepsina D
Scope note: Proteinasa intracelular presente en diversos tejidos. Tiene especificidad similar a la de la pepsina A, pero menor. La enzima interviene en el catabolismo del tejido cartilaginoso y conjuntivo. EC 3.4.23.5 (anteriormente EC 3.4.4.23).
Descriptor Portuguese: Catepsina D
Descriptor French: Cathepsine D
Tree number(s): D08.811.277.656.074.500.180
D08.811.277.656.224.187
D08.811.277.656.300.048.180
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002402
Scope note: An intracellular proteinase found in a variety of tissue. It has specificity similar to but narrower than that of pepsin A. The enzyme is involved in catabolism of cartilage and connective tissue. EC 3.4.23.5. (Formerly EC 3.4.4.23).
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.4.23.5
Previous Indexing: Cathepsins (1966-1984)
Public MeSH Note: 85
History Note: 85
DeCS ID: 29336
Unique ID: D002402
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1985/01/01
Date of Entry: 1984/05/24
Revision Date: 2009/07/06
Cathepsin D - Preferred
Concept UI M0003660
Scope note An intracellular proteinase found in a variety of tissue. It has specificity similar to but narrower than that of pepsin A. The enzyme is involved in catabolism of cartilage and connective tissue. EC 3.4.23.5. (Formerly EC 3.4.4.23).
Preferred term Cathepsin D



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