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Descriptor English: Complement C4a
Descriptor Spanish: Complemento C4a
Descriptor complemento C4a
Scope note: El fragmento más pequeño formado cuando el complemento C4 es desdoblado por el COMPLEMENTO C1S. Es una anafilotoxina que causa síntomas de hipersensibilidad inmediata (HIPERSENSIBILIDAD INMEDIATA) pero su actividad es más débil que la del COMPLMENTO C3A o COMPLEMENTO C5A.
Descriptor Portuguese: Complemento C4a
Descriptor French: Complément C4a
Entry term(s): C4a Complement
C4a, Complement
Complement 4a
Complement Component 4a
Complement, C4a
Component 4a, Complement
Tree number(s): D12.776.124.486.274.024.260
D12.776.124.486.274.350.250
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015934
Scope note: The smaller fragment formed when complement C4 is cleaved by COMPLEMENT C1S. It is an anaphylatoxin that causes symptoms of immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE) but its activity is weaker than that of COMPLEMENT C3A or COMPLEMENT C5A.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Immunologic Factors
Registry Number: 80295-49-4
CAS Type 1 Name: Complement C4a
Previous Indexing: Anaphylatoxins (1980-1982)
Complement 4 (1978-1989)
Public MeSH Note: 2006; see COMPLEMENT 4A 1990-2005
History Note: 2006 (1990)
DeCS ID: 24578
Unique ID: D015934
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1990/01/01
Date of Entry: 1989/05/25
Revision Date: 2005/06/30
Complement C4a - Preferred
Concept UI M0024379
Scope note The smaller fragment formed when complement C4 is cleaved by COMPLEMENT C1S. It is an anaphylatoxin that causes symptoms of immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE) but its activity is weaker than that of COMPLEMENT C3A or COMPLEMENT C5A.
Preferred term Complement C4a
Entry term(s) C4a Complement
C4a, Complement
Complement 4a
Complement Component 4a
Complement, C4a
Component 4a, Complement



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