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Descriptor in English: Erythromycin Ethylsuccinate
Descriptor in Spanish: Etilsuccinato de Eritromicina
Descriptor in Portuguese: Etilsuccinato de Eritromicina
Descriptor in French: Éthylsuccinate d'érythromycine
Entry term(s): E-Mycin E
EMycin E
EryPed
Erythroped
Ethyl Succinate, Eyrthromycin
Ethylsuccinate, Erythromycin
Eyrthromycin Ethyl Succinate
Monomycin
Pediamycin
Succinate, Eyrthromycin Ethyl
Wyamycin E
Tree number(s): D02.540.576.500.992.260
Scope note: A macrolide antibiotic, produced by Streptomyces erythreus. This compound is an ester of erythromycin base and succinic acid. It acts primarily as a bacteriostatic agent. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 90
DeCS UI: 24629
Descriptor UI: D015643
Date Established: 1990/01/01
Date of Entry: 1989/05/25
Revision Date: 2015/06/22
Erythromycin Ethylsuccinate - Preferred
Concept UI M0023980
Scope note A macrolide antibiotic, produced by Streptomyces erythreus. This compound is an ester of erythromycin base and succinic acid. It acts primarily as a bacteriostatic agent. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
Preferred term Erythromycin Ethylsuccinate
Entry term(s) Ethyl Succinate, Eyrthromycin
Ethylsuccinate, Erythromycin
Eyrthromycin Ethyl Succinate
Succinate, Eyrthromycin Ethyl
EryPed - Narrower
Concept UI M0352023
Preferred term EryPed
Wyamycin E - Narrower
Concept UI M0352020
Preferred term Wyamycin E
Monomycin - Narrower
Concept UI M0392827
Preferred term Monomycin
Pediamycin - Narrower
Concept UI M0352021
Preferred term Pediamycin
E-Mycin E - Narrower
Concept UI M0352024
Preferred term E-Mycin E
Entry term(s) EMycin E
Erythroped - Narrower
Concept UI M0352022
Preferred term Erythroped



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