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Descriptor in English: Clarithromycin
Descriptor in Spanish: Claritromicina
Descriptor in Portuguese: Claritromicina
Descriptor in French: Clarithromycine
Entry term(s): 6-O-Methylerythromycin
A 56268
A-56268
A56268
Biaxin
TE 031
TE-031
TE031
Tree number(s): D02.540.576.500.992.100
Scope note: A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Online Note: use CLARITHROMYCIN (NM) to search CLARITHROMYCIN 1987-92
History Note: 93; was CLARITHROMYCIN (NM) 1987-92
DeCS UI: 30785
Descriptor UI: D017291
Date Established: 1993/01/01
Date of Entry: 1992/05/07
Revision Date: 2015/06/22
Clarithromycin - Preferred
Concept UI M0026249
Scope note A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.
Preferred term Clarithromycin
Entry term(s) 6-O-Methylerythromycin
TE-031 - Narrower
Concept UI M0352014
Preferred term TE-031
Entry term(s) TE 031
TE031
A-56268 - Narrower
Concept UI M0352016
Preferred term A-56268
Entry term(s) A 56268
A56268
Biaxin - Narrower
Concept UI M0352015
Preferred term Biaxin



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