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Descriptor English: Erythromycin
Descriptor Spanish: Eritromicina
Descriptor eritromicina
Scope note: Antibiótico macrólido bacteriostático producido por Streptomyces erythreus. Se considera que la eritromicina es su principal componente activo. En los organismos sensibles inhibe la síntesis de proteínas al unirse a las subunidades ribosómicas 50S. Este proceso de unión inhibe la actividad peptidil trransferasa e interfiere en la translocación de los aminoácidos durante la traducción y ensamblaje de las proteínas.
Descriptor Portuguese: Eritromicina
Descriptor French: Érythromycine
Entry term(s): Erycette
Erymax
Erythromycin A
Erythromycin C
Erythromycin Lactate
Erythromycin Phosphate
Ilotycin
Lactate, Erythromycin
Phosphate, Erythromycin
T Stat
T-Stat
TStat
Tree number(s): D02.540.576.500.992
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004917
Scope note: A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Gastrointestinal Agents
Protein Synthesis Inhibitors
Registry Number: 63937KV33D
DeCS ID: 28027
Unique ID: D004917
NLM Classification: QV 350.5.E7
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/06/28
Erythromycin - Preferred
Concept UI M0007715
Scope note A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
Preferred term Erythromycin
Entry term(s) Erythromycin A
Erythromycin Phosphate - Narrower
Concept UI M0007717
Preferred term Erythromycin Phosphate
Entry term(s) Phosphate, Erythromycin
Erythromycin Lactate - Narrower
Concept UI M0007716
Preferred term Erythromycin Lactate
Entry term(s) Lactate, Erythromycin
T-Stat - Narrower
Concept UI M0007722
Preferred term T-Stat
Entry term(s) T Stat
TStat
Erymax - Narrower
Concept UI M0007721
Preferred term Erymax
Erythromycin C - Related but not broader or narrower
Concept UI M0007718
Preferred term Erythromycin C
Erycette - Narrower
Concept UI M0007720
Preferred term Erycette
Ilotycin - Narrower
Concept UI M0007719
Preferred term Ilotycin



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