| Descriptor English: | Mefloquine | ||||
| Descriptor Spanish: | Mefloquina 
 | ||||
| Descriptor Portuguese: | Mefloquina | ||||
| Descriptor French: | Méfloquine | ||||
| Entry term(s): | Lariam Mefloquine Hydrochloride Mephloquine Ro 21 5998 001 Ro-21-5998-001 Ro215998001 WR 142,490 WR 177,602 WR-142,490 WR-177,602 WR142,490 WR177,602 | ||||
| Tree number(s): | D03.633.100.810.410 | ||||
| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D015767 | ||||
| Scope note: | A phospholipid-interacting antimalarial drug (ANTIMALARIALS). It is very effective against PLASMODIUM FALCIPARUM with very few side effects. | ||||
| Allowable Qualifiers: | AA                                                            analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine | ||||
| Pharm Action: | Antimalarials | ||||
| Registry Number: | TML814419R | ||||
| CAS Type 1 Name: | 4-Quinolinemethanol, alpha-2-piperidinyl-2,8-bis(trifluoromethyl)-, (R*,S*)-(+-)- | ||||
| Previous Indexing: | Antimalarials (1966-1989) Quinolines (1966-1989) | ||||
| Public MeSH Note: | 90 | ||||
| History Note: | 90 | ||||
| DeCS ID: | 24777 | ||||
| Unique ID: | D015767 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 1990/01/01 | ||||
| Date of Entry: | 1989/05/25 | ||||
| Revision Date: | 2017/05/24 | 
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                                    - 
                                        CHEMICALS AND DRUGS
 
 Heterocyclic Compounds [D03]Heterocyclic Compounds
|  | 
                        
                                                                    
                        Mefloquine                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                                                                    
                        WR-177,602                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Ro-21-5998-001                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        WR-142,490                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Lariam                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Mefloquine Hydrochloride                                            
                                        - Narrower                                        
                                                                
                                
                        
                        
                    
                    
                
                | Concept UI | M0024162 | 
| Scope note | A phospholipid-interacting antimalarial drug (ANTIMALARIALS). It is very effective against PLASMODIUM FALCIPARUM with very few side effects. | 
| Preferred term | Mefloquine | 
| Entry term(s) | Mephloquine | 
| Concept UI | M0374654 | 
| Preferred term | WR-177,602 | 
| Entry term(s) | WR 177,602 WR177,602 | 
| Concept UI | M0353901 | 
| Preferred term | Ro-21-5998-001 | 
| Entry term(s) | Ro 21 5998 001 Ro215998001 | 
| Concept UI | M0353902 | 
| Preferred term | WR-142,490 | 
| Entry term(s) | WR 142,490 WR142,490 | 
| Concept UI | M0024164 | 
| Preferred term | Lariam | 
| Concept UI | M0024163 | 
| Preferred term | Mefloquine Hydrochloride | 
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