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Descriptor English: Immunotoxins
Descriptor Spanish: Inmunotoxinas
Descriptor inmunotoxinas
Entry term(s) afinotoxina
afinotoxinas
conjugado anticuerpo monoclonal-toxina
conjugado anticuerpo-toxina
conjugado citotoxina-anticuerpo
conjugado de toxina-anticuerpo
conjugados anticuerpo-toxina
conjugados citotoxina-anticuerpo
conjugados de toxinas
conjugados toxina-anticuerpo
híbrido anticuerpo-toxina
híbrido toxina-anticuerpo
híbridos de anticuerpo-toxina
híbridos toxina-anticuerpo
toxina dirigida
toxinas diana
transportadores de toxinas
Scope note: Conjugados semisintéticos de diversas moléculas tóxicas, que incluyen ISÓTOPOS RADIOACTIVOS y TOXINAS de bacterias o de plantas, con sustancias inmunitarias específicas tales como INMUNOGLOBULINAS, ANTICUERPOS MONOCLONALES y ANTÍGENOS. La sustancia inmunitaria antitumoral o antivírica transporta la toxina hasta el tumor o célula infectada en donde la toxina ejerce su efecto tóxico.
Descriptor Portuguese: Imunotoxinas
Descriptor French: Immunotoxines
Entry term(s): Affinotoxin
Affinotoxins
Antibody Toxin Conjugate
Antibody Toxin Conjugates
Antibody Toxin Hybrid
Antibody Toxin Hybrids
Antibody-Toxin Conjugate
Antibody-Toxin Conjugate, Monoclonal
Antibody-Toxin Conjugates
Antibody-Toxin Conjugates, Monoclonal
Antibody-Toxin Hybrid
Antibody-Toxin Hybrids
Carrier, Toxin
Carriers, Toxin
Chimeric Toxin
Chimeric Toxins
Conjugate, Antibody-Toxin
Conjugate, Cytotoxin-Antibody
Conjugate, Monoclonal Antibody-Toxin
Conjugate, Toxin
Conjugate, Toxin-Antibody
Conjugates, Antibody-Toxin
Conjugates, Cytotoxin-Antibody
Conjugates, Monoclonal Antibody-Toxin
Conjugates, Toxin
Conjugates, Toxin-Antibody
Cytotoxin Antibody Conjugate
Cytotoxin Antibody Conjugates
Cytotoxin-Antibody Conjugate
Cytotoxin-Antibody Conjugates
Hybrid, Antibody-Toxin
Hybrid, Toxin-Antibody
Hybrids, Antibody-Toxin
Hybrids, Toxin-Antibody
Immunotoxin
Monoclonal Antibody Toxin Conjugate
Monoclonal Antibody Toxin Conjugates
Monoclonal Antibody-Toxin Conjugate
Monoclonal Antibody-Toxin Conjugates
Targeted Toxin
Targeted Toxins
Toxin Antibody Conjugate
Toxin Antibody Conjugates
Toxin Antibody Hybrid
Toxin Antibody Hybrids
Toxin Carrier
Toxin Carriers
Toxin Conjugate
Toxin Conjugates
Toxin, Chimeric
Toxin, Targeted
Toxin-Antibody Conjugate
Toxin-Antibody Conjugates
Toxin-Antibody Hybrid
Toxin-Antibody Hybrids
Toxins, Chimeric
Toxins, Targeted
Tree number(s): D12.776.124.790.651.114.580.450
D12.776.377.715.548.114.580.450
D27.505.696.477.266.500
D27.888.569.279
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000922
Scope note: Semisynthetic conjugates of various toxic molecules, including RADIOACTIVE ISOTOPES and bacterial or plant toxins, with specific immune substances such as IMMUNOGLOBULINS; MONOCLONAL ANTIBODIES; and ANTIGENS. The antitumor or antiviral immune substance carries the toxin to the tumor or infected cell where the toxin exerts its poisonous effect.
Annotation: coordinate IM with specific toxin (IM) + specific immune substance (NIM)
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Immunologic Factors
Previous Indexing: Antibodies, Monoclonal (1982-1986)
Antigens, Surface (1979-1986)
Antitoxins (1966-1986)
Cytotoxicity, Immunologic (1978-1986)
Ricin (1978-1985)
Public MeSH Note: 90; was ANTIBODY-TOXIN CONJUGATES 1987-89
Online Note: use IMMUNOTOXINS to search ANTIBODY-TOXIN CONJUGATES 1987-89
History Note: 90; was ANTIBODY-TOXIN CONJUGATES 1987-89
DeCS ID: 28229
Unique ID: D000922
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1987/01/01
Date of Entry: 1986/03/25
Revision Date: 2020/05/27
Immunotoxins - Preferred
Concept UI M0001373
Scope note Semisynthetic conjugates of various toxic molecules, including RADIOACTIVE ISOTOPES and bacterial or plant toxins, with specific immune substances such as IMMUNOGLOBULINS; MONOCLONAL ANTIBODIES; and ANTIGENS. The antitumor or antiviral immune substance carries the toxin to the tumor or infected cell where the toxin exerts its poisonous effect.
Preferred term Immunotoxins
Entry term(s) Affinotoxin
Affinotoxins
Antibody Toxin Conjugate
Antibody Toxin Conjugates
Antibody Toxin Hybrid
Antibody Toxin Hybrids
Antibody-Toxin Conjugate
Antibody-Toxin Conjugate, Monoclonal
Antibody-Toxin Conjugates
Antibody-Toxin Conjugates, Monoclonal
Antibody-Toxin Hybrid
Antibody-Toxin Hybrids
Conjugate, Antibody-Toxin
Conjugate, Cytotoxin-Antibody
Conjugate, Monoclonal Antibody-Toxin
Conjugate, Toxin-Antibody
Conjugates, Antibody-Toxin
Conjugates, Cytotoxin-Antibody
Conjugates, Monoclonal Antibody-Toxin
Conjugates, Toxin-Antibody
Cytotoxin Antibody Conjugate
Cytotoxin Antibody Conjugates
Cytotoxin-Antibody Conjugate
Cytotoxin-Antibody Conjugates
Hybrid, Antibody-Toxin
Hybrid, Toxin-Antibody
Hybrids, Antibody-Toxin
Hybrids, Toxin-Antibody
Immunotoxin
Monoclonal Antibody Toxin Conjugate
Monoclonal Antibody Toxin Conjugates
Monoclonal Antibody-Toxin Conjugate
Monoclonal Antibody-Toxin Conjugates
Toxin Antibody Conjugate
Toxin Antibody Conjugates
Toxin Antibody Hybrid
Toxin Antibody Hybrids
Toxin-Antibody Conjugate
Toxin-Antibody Conjugates
Toxin-Antibody Hybrid
Toxin-Antibody Hybrids
Targeted Toxins - Broader
Concept UI M0001375
Preferred term Targeted Toxins
Entry term(s) Targeted Toxin
Toxin, Targeted
Toxins, Targeted
Toxins, Chimeric - Broader
Concept UI M0001374
Preferred term Toxins, Chimeric
Entry term(s) Carrier, Toxin
Carriers, Toxin
Chimeric Toxin
Chimeric Toxins
Conjugate, Toxin
Conjugates, Toxin
Toxin Carrier
Toxin Carriers
Toxin Conjugate
Toxin Conjugates
Toxin, Chimeric



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