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Descriptor English: Irritants
Descriptor Spanish: Irritantes
Descriptor Portuguese: Irritantes
Descriptor French: Irritants
Entry term(s): Counterirritant
Counterirritants
Irritant
Pustulant
Pustulants
Rubefacient
Rubefacients
Vesicant
Vesicants
Tree number(s): D27.720.400
D27.888.569.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007509
Scope note: Drugs that act locally on cutaneous or mucosal surfaces to produce inflammation; those that cause redness due to hyperemia are rubefacients; those that raise blisters are vesicants and those that penetrate sebaceous glands and cause abscesses are pustulants; tear gases and mustard gases are also irritants.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Online Note: use IRRITANTS to search RUBEFACIENTS & VESICANTS 1966-79
History Note: RUBEFACIENTS & VESICANTS were see under IRRITANTS 1963-79
DeCS ID: 7676
Unique ID: D007509
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1960/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27
Irritants - Preferred
Concept UI M0011729
Scope note Drugs that act locally on cutaneous or mucosal surfaces to produce inflammation; those that cause redness due to hyperemia are rubefacients; those that raise blisters are vesicants and those that penetrate sebaceous glands and cause abscesses are pustulants; tear gases and mustard gases are also irritants.
Preferred term Irritants
Entry term(s) Irritant
Vesicants - Narrower
Concept UI M0011732
Preferred term Vesicants
Entry term(s) Vesicant
Counterirritants - Related but not broader or narrower
Concept UI M0011728
Preferred term Counterirritants
Entry term(s) Counterirritant
Rubefacients - Narrower
Concept UI M0011731
Preferred term Rubefacients
Entry term(s) Rubefacient
Pustulants - Narrower
Concept UI M0011730
Preferred term Pustulants
Entry term(s) Pustulant



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