| Descriptor English: | Cholinesterase Inhibitors | ||||||
| Descriptor Spanish: |
Inhibidores de la Colinesterasa
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| Descriptor Portuguese: | Inibidores da Colinesterase | ||||||
| Descriptor French: | Anticholinestérasiques | ||||||
| Entry term(s): |
Acetylcholinesterase Inhibitor Acetylcholinesterase Inhibitors Agent, Anticholinesterase Agents, Anticholinesterase Anti Cholinesterase Anti Cholinesterases Anti-Cholinesterase Anti-Cholinesterases Anticholinesterase Anticholinesterase Agent Anticholinesterase Agents Anticholinesterase Drug Anticholinesterase Drugs Anticholinesterases Cholinesterase Inhibitor Cholinesterase Inhibitors, Irreversible Cholinesterase Inhibitors, Reversible Drug, Anticholinesterase Drugs, Anticholinesterase Inhibitor, Acetylcholinesterase Inhibitor, Cholinesterase Inhibitors, Acetylcholinesterase Inhibitors, Cholinesterase Inhibitors, Irreversible Cholinesterase Inhibitors, Reversible Cholinesterase Irreversible Cholinesterase Inhibitors Reversible Cholinesterase Inhibitors |
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| Tree number(s): |
D27.505.519.389.275 D27.505.519.625.120.300 D27.505.696.577.120.300 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D002800 | ||||||
| Scope note: | Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Public MeSH Note: | 65; CHOLINESTERASE INHIBITORS, IRREVERSIBLE & CHOLINESTERASE INHIBITORS, REVERSIBLE were see under CHOLINESTERASE INHIBITORS 1975-83; CHOLINESTERASE INHIBITORS, ORGANIC was see PHOSPHORUS POISONS, ORGANIC 1963-64 (PHOSPHORUS POISONS, ORGANIC deleted 1965) |
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| Online Note: | use CHOLINESTERASE INHIBITORS to search CHOLINESTERASE INHIBITORS, IRREVERSIBLE & CHOLINESTERASE INHIBITORS, REVERSIBLE 1971-83 (as Prov 1971-74) |
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| History Note: | 65; CHOLINESTERASE INHIBITORS, IRREVERSIBLE & CHOLINESTERASE INHIBITORS, REVERSIBLE were see under CHOLINESTERASE INHIBITORS 1975-83, were Prov 1971-74; CHOLINESTERASE INHIBITORS, ORGANIC was see PHOSPHORUS POISONS, ORGANIC 1963-64 (PHOSPHORUS POISONS, ORGANIC deleted 1965) |
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| Entry Version: | CHOLINESTERASE INHIB |
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| Related: |
Insecticides
MeSH | ||||||
| DeCS ID: | 2850 | ||||||
| Unique ID: | D002800 | ||||||
| NLM Classification: | QV 124 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1965/01/01 | ||||||
| Date of Entry: | 1999/01/01 | ||||||
| Revision Date: | 2020/05/27 |
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CHEMICALS AND DRUGS
Chemical Actions and Uses [D27]Chemical Actions and Uses -
CHEMICALS AND DRUGS
Chemical Actions and Uses [D27]Chemical Actions and Uses -
CHEMICALS AND DRUGS
Chemical Actions and Uses [D27]Chemical Actions and Uses
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Cholinesterase Inhibitors
- Preferred
Cholinesterase Inhibitors, Irreversible
- Narrower
Cholinesterase Inhibitors, Reversible
- Narrower
Acetylcholinesterase Inhibitors
- Narrower
| Concept UI |
M0004295 |
| Scope note | Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system. |
| Preferred term | Cholinesterase Inhibitors |
| Entry term(s) |
Agent, Anticholinesterase Agents, Anticholinesterase Anti Cholinesterase Anti Cholinesterases Anti-Cholinesterase Anti-Cholinesterases Anticholinesterase Anticholinesterase Agent Anticholinesterase Agents Anticholinesterase Drug Anticholinesterase Drugs Anticholinesterases Cholinesterase Inhibitor Drug, Anticholinesterase Drugs, Anticholinesterase Inhibitor, Cholinesterase Inhibitors, Cholinesterase |
| Concept UI |
M0004296 |
| Preferred term | Cholinesterase Inhibitors, Irreversible |
| Entry term(s) |
Inhibitors, Irreversible Cholinesterase Irreversible Cholinesterase Inhibitors |
| Concept UI |
M0004297 |
| Preferred term | Cholinesterase Inhibitors, Reversible |
| Entry term(s) |
Inhibitors, Reversible Cholinesterase Reversible Cholinesterase Inhibitors |
| Concept UI |
M0004294 |
| Preferred term | Acetylcholinesterase Inhibitors |
| Entry term(s) |
Acetylcholinesterase Inhibitor Inhibitor, Acetylcholinesterase Inhibitors, Acetylcholinesterase |
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