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Descriptor English: HIV Long Terminal Repeat
Descriptor Spanish: Duplicado del Terminal Largo de VIH
Descriptor repetición terminal larga del VIH
Entry term(s) elemento regulador negativo VIH
región de respuesta transactivadora del VIH
repetición terminal larga del virus de la inmunodeficiencia humana
sitio de unión a Sp1 del VIH
Scope note: Secuencias reguladoras importantes para la replicación vírica que se encuentran a cada extremo del genoma del VIH. La repetición terminal larga (en inglés LTR) incluye el POTENCIADOR VIH, promotores y otras secuencias del VIH. Son regiones específicas de la repetición terminal larga un elemento regulador negativo (ERN), los sitios de unión NF-kappa B, los sitios de unión Sp1, la TATA BOX y el elemento de respuesta transactivador (RTA). La unión de proteínas celulares y víricas a estas regiones regula la transcripción del VIH.
Descriptor Portuguese: Repetição Terminal Longa de HIV
Descriptor French: Répétition terminale longue du VIH
Entry term(s): HIV 1 LTR
HIV Negative Regulatory Element
HIV Sp1 Binding Site
HIV Sp1-Binding Site
HIV Sp1-Binding Sites
HIV TAR Element
HIV TAR Elements
HIV Trans Acting Responsive Region
HIV Trans-Acting Responsive Region
HIV-1 LTR
Human Immunodeficiency Virus LTR
Human Immunodeficiency Virus Long Terminal Repeat
LTR, HIV-1
LTR, Human Immunodeficiency Virus
Long Terminal Repeat, HIV
Negative Regulatory Element, HIV
Sp1 Binding Site, HIV
Sp1-Binding Site, HIV
Sp1-Binding Sites, HIV
TAR Element, HIV
TAR Elements, HIV
Trans Acting Responsive Region, HIV
Trans Activation Responsive Element, HIV
Trans Activation Responsive Region, HIV
Trans-Acting Responsive Region, HIV
Trans-Activation Responsive Element, HIV
Trans-Activation Responsive Region, HIV
Tree number(s): G02.111.570.080.708.850.400
G05.360.080.708.850.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016325
Scope note: Regulatory sequences important for viral replication that are located on each end of the HIV genome. The LTR includes the HIV ENHANCER, promoter, and other sequences. Specific regions in the LTR include the negative regulatory element (NRE), NF-kappa B binding sites , Sp1 binding sites, TATA BOX, and trans-acting responsive element (TAR). The binding of both cellular and viral proteins to these regions regulates HIV transcription.
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Repetitive Sequences, Nucleic Acid (1986-1990)
Public MeSH Note: 91
History Note: 91
Entry Version: HIV LTR
Related: Gene Products, nef MeSH
Gene Products, tat MeSH
HIV Enhancer MeSH
Sp1 Transcription Factor MeSH
DeCS ID: 28980
Unique ID: D016325
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1990/06/28
Revision Date: 2008/07/08
HIV Long Terminal Repeat - Preferred
Concept UI M0024948
Scope note Regulatory sequences important for viral replication that are located on each end of the HIV genome. The LTR includes the HIV ENHANCER, promoter, and other sequences. Specific regions in the LTR include the negative regulatory element (NRE), NF-kappa B binding sites , Sp1 binding sites, TATA BOX, and trans-acting responsive element (TAR). The binding of both cellular and viral proteins to these regions regulates HIV transcription.
Preferred term HIV Long Terminal Repeat
Entry term(s) Human Immunodeficiency Virus LTR
Human Immunodeficiency Virus Long Terminal Repeat
LTR, Human Immunodeficiency Virus
Long Terminal Repeat, HIV
Trans-Acting Responsive Region, HIV - Narrower
Concept UI M0024951
Preferred term Trans-Acting Responsive Region, HIV
Entry term(s) HIV TAR Element
HIV TAR Elements
HIV Trans Acting Responsive Region
HIV Trans-Acting Responsive Region
TAR Element, HIV
TAR Elements, HIV
Trans Acting Responsive Region, HIV
Trans Activation Responsive Element, HIV
Trans Activation Responsive Region, HIV
Trans-Activation Responsive Element, HIV
Trans-Activation Responsive Region, HIV
Sp1-Binding Site, HIV - Narrower
Concept UI M0024950
Preferred term Sp1-Binding Site, HIV
Entry term(s) HIV Sp1 Binding Site
HIV Sp1-Binding Site
HIV Sp1-Binding Sites
Sp1 Binding Site, HIV
Sp1-Binding Sites, HIV
HIV-1 LTR - Narrower
Concept UI M0024952
Preferred term HIV-1 LTR
Entry term(s) HIV 1 LTR
LTR, HIV-1
Negative Regulatory Element, HIV - Narrower
Concept UI M0024949
Preferred term Negative Regulatory Element, HIV
Entry term(s) HIV Negative Regulatory Element



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