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Descriptor English: Gene Products, tat
Descriptor Spanish: Productos del Gen tat
Descriptor productos del gen tat
Entry term(s) proteína tat
Scope note: Factores de transcripción que actúan en trans y son producidos por retrovirus, como el VIH. Son proteínas nucleares cuya expresión es necesaria para la replicación viral. La proteína tat estimula la síntesis de ARN guiada por la REPETICIÓN TERMINAL LARGA de proteínas virales reguladoras y estructurales. El término tat es la abreviatura de transactivación de la transcripción.
Descriptor Portuguese: Produtos do Gene tat
Descriptor French: Protéines du gène tat
Entry term(s): Gene Product, tat
tat Gene Product
tat Gene Products
tat Protein
Tree number(s): D12.776.260.755.199
D12.776.930.900.199
D12.776.964.900.750.750
D12.776.964.925.984.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015696
Scope note: Trans-acting transcription factors produced by retroviruses such as HIV. They are nuclear proteins whose expression is required for viral replication. The tat protein stimulates LONG TERMINAL REPEAT-driven RNA synthesis for both viral regulatory and viral structural proteins. Tat stands for trans-activation of transcription.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Transcription Factors (1988-1989)
Public MeSH Note: 91; was see under TRANS-ACTIVATORS 1990
History Note: 91(90); was see under TRANS-ACTIVATORS 1990
DeCS ID: 24679
Unique ID: D015696
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1989/07/07
Revision Date: 2007/07/09
Gene Products, tat - Preferred
Concept UI M0024076
Scope note Trans-acting transcription factors produced by retroviruses such as HIV. They are nuclear proteins whose expression is required for viral replication. The tat protein stimulates LONG TERMINAL REPEAT-driven RNA synthesis for both viral regulatory and viral structural proteins. Tat stands for trans-activation of transcription.
Preferred term Gene Products, tat
Entry term(s) Gene Product, tat
tat Gene Product
tat Gene Products
tat Protein



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