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Descriptor English: RNA, Antisense
Descriptor Spanish: ARN sin Sentido
Descriptor ARN antiparalelo
Entry term(s) ARN antisentido
Scope note: Moléculas de ARN que se hibridan con secuencias complementarias tanto en el ARN como en el ADN y alteran la función de estas últimas. Los ARNs antisentido endógenos actúan como reguladores de la expresión génica mediante diversos mecanismos. Los ARNs antisentido sintéticos se utilizan para afectar el funcionamiento de genes específicos en la investigación o con fines terapéuticos.
Descriptor Portuguese: RNA Antissenso
Descriptor French: ARN antisens
Tree number(s): D13.150.650
D13.444.600.150.760
D13.444.735.150
D27.720.470.530.600.150.760
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016372
Scope note: RNA molecules which hybridize to complementary sequences in either RNA or DNA altering the function of the latter. Endogenous antisense RNAs function as regulators of gene expression by a variety of mechanisms. Synthetic antisense RNAs are used to effect the functioning of specific genes for investigative or therapeutic purposes.
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine
DeCS ID: 29111
Unique ID: D016372
NLM Classification: QU 58.7
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1990/05/29
Revision Date: 2011/06/24
ARN antisens - Preferred
Concept UI M0025050
Preferred term ARN antisens



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