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Descriptor English: DNA, Antisense
Descriptor Spanish: ADN sin Sentido
Descriptor Portuguese: DNA Antissenso
Descriptor French: ADN antisens
Entry term(s): Anti Sense DNA
Anti-Sense DNA
Antisense DNA
DNA, Anti-Sense
Tree number(s): D13.150.200
D13.444.308.150
D13.444.600.150.200
D27.720.470.530.600.150.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016373
Scope note: DNA that is complementary to the sense strand. (The sense strand has the same sequence as the mRNA transcript. The antisense strand is the template for mRNA synthesis.) Synthetic antisense DNAs are used to hybridize to complementary sequences in target RNAs or DNAs to effect the functioning of specific genes for investigative or therapeutic purposes.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: DNA (1988-1990)
Public MeSH Note: 91
History Note: 91
DeCS ID: 28912
Unique ID: D016373
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1990/05/25
Revision Date: 2003/07/09
DNA, Antisense - Preferred
Concept UI M0025051
Scope note DNA that is complementary to the sense strand. (The sense strand has the same sequence as the mRNA transcript. The antisense strand is the template for mRNA synthesis.) Synthetic antisense DNAs are used to hybridize to complementary sequences in target RNAs or DNAs to effect the functioning of specific genes for investigative or therapeutic purposes.
Preferred term DNA, Antisense
Entry term(s) Anti Sense DNA
Anti-Sense DNA
Antisense DNA
DNA, Anti-Sense



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