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Descriptor English: Creutzfeldt-Jakob Syndrome
Descriptor Spanish: Síndrome de Creutzfeldt-Jakob
Descriptor síndrome de Creutzfeldt-Jakob
Entry term(s) encefalopatía espongiforme subaguda
variante nueva de la enfermedad de Creutzfeldt-Jakob
Scope note: Encefalopatía transmisible infrecuente con mayor prevalencia en las edades de 50 y 70 años. Los individuos afectados pueden presentar trastornos del sueño, cambios de personalidad, ATAXIA, AFASIA, pérdida visual, debilidad, atrofia muscular, MIOCLONÍA, demencia progresiva, y muerte en el transcurso de un año después del comienzo de la enfermedad. Se han descrito una forma familiar que muestra herencia autosómica dominante y una variante nueva de ECJ (asociada potencialmente con ENCEFALOPATÍA ESPONGIFORME BOVINA). Las características anatomopatológicas incluyen una importante degeneración espongiforme de la cortical cerebelosa y cerebral y la presencia de PRIONES. (N Engl J Med, 1998 Dec 31;339(27))
Descriptor Portuguese: Síndrome de Creutzfeldt-Jakob
Descriptor French: Maladie de Creutzfeldt-Jakob
Entry term(s): CJD (Creutzfeldt Jakob Disease)
CJD (Creutzfeldt-Jakob Disease)
Creutzfeldt Jacob Disease
Creutzfeldt Jakob Disease
Creutzfeldt Jakob Disease, Familial
Creutzfeldt Jakob Disease, New Variant
Creutzfeldt Jakob Disease, Variant
Creutzfeldt Jakob Syndrome
Creutzfeldt-Jakob Disease
Creutzfeldt-Jakob Disease, Familial
Creutzfeldt-Jakob Disease, New Variant
Creutzfeldt-Jakob Disease, Variant
Creutzfeldt-Jakob Diseases, Familial
Disease, Creutzfeldt Jacob
Disease, Creutzfeldt-Jakob
Disease, Familial Creutzfeldt-Jakob
Disease, Jakob-Creutzfeldt
Encephalopathies, Subacute Spongiform
Encephalopathy, Subacute Spongiform
Familial Creutzfeldt Jakob Disease
Familial Creutzfeldt-Jakob Disease
Familial Creutzfeldt-Jakob Diseases
Jacob Disease, Creutzfeldt
Jakob Creutzfeldt Disease
Jakob Creutzfeldt Syndrome
Jakob-Creutzfeldt Disease
Jakob-Creutzfeldt Syndrome
New Variant Creutzfeldt Jakob Disease
New Variant Creutzfeldt-Jakob Disease
Spongiform Encephalopathies, Subacute
Spongiform Encephalopathy, Subacute
Subacute Spongiform Encephalopathies
Subacute Spongiform Encephalopathy
Syndrome, Creutzfeldt-Jakob
Syndrome, Jakob-Creutzfeldt
V CJD (Variant Creutzfeldt Jakob Disease)
V-CJD (Variant-Creutzfeldt-Jakob Disease)
Variant Creutzfeldt Jakob Disease
Variant Creutzfeldt-Jakob Disease
Tree number(s): C01.207.800.230
C10.228.140.380.165
C10.228.228.800.230
F03.615.400.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007562
Scope note: A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
TM transmission
UR urine
VE veterinary
VI virology
Previous Indexing: Central Nervous System Diseases (1966-1968)
Public MeSH Note: 1991; see JAKOB-CREUTZFELDT SYNDROME 1981-1990, see CREUTZFELDT-JAKOB DISEASE 1973-1980
History Note: 1991; use JAKOB-CREUTZFELDT SYNDROME 1981-1990, use CREUTZFELDT-JAKOB DISEASE 1969-1980
DeCS ID: 29254
Unique ID: D007562
NLM Classification: WL 301
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2015/06/03
Creutzfeldt-Jakob Syndrome - Preferred
Concept UI M0011818
Scope note A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))
Preferred term Creutzfeldt-Jakob Syndrome
Entry term(s) CJD (Creutzfeldt Jakob Disease)
CJD (Creutzfeldt-Jakob Disease)
Creutzfeldt Jacob Disease
Creutzfeldt Jakob Disease
Creutzfeldt Jakob Syndrome
Creutzfeldt-Jakob Disease
Disease, Creutzfeldt Jacob
Disease, Creutzfeldt-Jakob
Disease, Jakob-Creutzfeldt
Encephalopathies, Subacute Spongiform
Encephalopathy, Subacute Spongiform
Jacob Disease, Creutzfeldt
Jakob Creutzfeldt Disease
Jakob Creutzfeldt Syndrome
Jakob-Creutzfeldt Disease
Jakob-Creutzfeldt Syndrome
Spongiform Encephalopathies, Subacute
Spongiform Encephalopathy, Subacute
Subacute Spongiform Encephalopathies
Subacute Spongiform Encephalopathy
Syndrome, Creutzfeldt-Jakob
Syndrome, Jakob-Creutzfeldt
Creutzfeldt-Jakob Disease, Familial - Narrower
Concept UI M0334707
Preferred term Creutzfeldt-Jakob Disease, Familial
Entry term(s) Creutzfeldt Jakob Disease, Familial
Creutzfeldt-Jakob Diseases, Familial
Disease, Familial Creutzfeldt-Jakob
Familial Creutzfeldt Jakob Disease
Familial Creutzfeldt-Jakob Disease
Familial Creutzfeldt-Jakob Diseases
New Variant Creutzfeldt-Jakob Disease - Narrower
Concept UI M0011819
Preferred term New Variant Creutzfeldt-Jakob Disease
Entry term(s) Creutzfeldt Jakob Disease, New Variant
Creutzfeldt Jakob Disease, Variant
Creutzfeldt-Jakob Disease, New Variant
Creutzfeldt-Jakob Disease, Variant
New Variant Creutzfeldt Jakob Disease
V CJD (Variant Creutzfeldt Jakob Disease)
V-CJD (Variant-Creutzfeldt-Jakob Disease)
Variant Creutzfeldt Jakob Disease
Variant Creutzfeldt-Jakob Disease



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