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Descriptor English: Clathrin
Descriptor Spanish: Clatrina
Descriptor clatrina
Scope note: Principal proteína estructural que tapiza las VESÍCULAS CUBIERTAS que desempeñan un papel clave en el transporte intracelular entre los organelos membranosos. Cada molécula de clatrina consta de tres cadenas ligeras (CADENAS LIGERAS DE CLATRINA) y tres cadenas pesadas (CADENAS PESADAS DE CLATRINA) que forman una estructura llamada triscele. La clatrina también interactúa con las proteínas citoesqueléticas.
Descriptor Portuguese: Clatrina
Descriptor French: Clathrine
Tree number(s): D12.776.543.990.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002966
Scope note: The main structural coat protein of COATED VESICLES which play a key role in the intracellular transport between membranous organelles. Each molecule of clathrin consists of three light chains (CLATHRIN LIGHT CHAINS) and three heavy chains (CLATHRIN HEAVY CHAINS) that form a structure called a triskelion. Clathrin also interacts with cytoskeletal proteins.
Annotation: CLATHRIN ASSEMBLY PROTEINS see ADAPTOR PROTEINS, VESICULAR TRANSPORT is available
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Membrane Proteins (1977-1983)
Proteins (1966-1976)
Public MeSH Note: 84
History Note: 84
DeCS ID: 2991
Unique ID: D002966
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1984/01/01
Date of Entry: 1983/05/31
Revision Date: 2015/06/23
Clathrin - Preferred
Concept UI M0004541
Scope note The main structural coat protein of COATED VESICLES which play a key role in the intracellular transport between membranous organelles. Each molecule of clathrin consists of three light chains (CLATHRIN LIGHT CHAINS) and three heavy chains (CLATHRIN HEAVY CHAINS) that form a structure called a triskelion. Clathrin also interacts with cytoskeletal proteins.
Preferred term Clathrin



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