| Descriptor English: | Dynamins | ||||||
| Descriptor Spanish: |
Dinaminas
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| Descriptor Portuguese: | Dinaminas | ||||||
| Descriptor French: | Dynamines | ||||||
| Entry term(s): |
Dephosphin Dynamin Dynamin K44A Dynamin, Alanine44 Substituted With Lysine Dynamin, GTPase-Deficient Dynamin, Mutated Form, K44A GTPase Deficient Dynamin GTPase-Deficient Dynamin |
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| Tree number(s): |
D08.811.277.040.330.200 D12.776.220.600.450.200 D12.776.543.990.400 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D034281 | ||||||
| Scope note: | A family of high molecular weight GTP phosphohydrolases that play a direct role in vesicle transport. They associate with microtubule bundles (MICROTUBULES) and are believed to produce mechanical force via a process linked to GTP hydrolysis. This enzyme was formerly listed as EC 3.6.1.50. |
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| Annotation: | general or unspecified; prefer specifics |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 3.6.5.5 | ||||||
| Previous Indexing: |
Ca(2+) Mg(2+)-ATPase (1989-1994) GTP Phosphohydrolases (1994-2002) |
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| Public MeSH Note: | 2003; DYNAMIN (now DYNAMINS) was indexed under GTP PHOSPHOHYDROLASES 1 1994-2002 & CA(2+) MG(2+)-ATPASE 1989-1993 |
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| History Note: | 2003; use DYNAMINS (NM) 1989-2002 |
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| DeCS ID: | 37318 | ||||||
| Unique ID: | D034281 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2003/01/01 | ||||||
| Date of Entry: | 2002/07/03 | ||||||
| Revision Date: | 2005/06/30 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Dynamins
- Preferred
GTPase-Deficient Dynamin
- Narrower
| Concept UI |
M0171126 |
| Scope note | A family of high molecular weight GTP phosphohydrolases that play a direct role in vesicle transport. They associate with microtubule bundles (MICROTUBULES) and are believed to produce mechanical force via a process linked to GTP hydrolysis. This enzyme was formerly listed as EC 3.6.1.50. |
| Preferred term | Dynamins |
| Entry term(s) |
Dephosphin Dynamin |
| Concept UI |
M0356790 |
| Scope note | Dynamins that contain an alanine in position 44 instead of lysine. The amino acid substitution causes the protein to be GTPase-deficient and unable to function normally in the cell. GTPase-deficient dynamins are used experimentally to study dynamin function. |
| Preferred term | GTPase-Deficient Dynamin |
| Entry term(s) |
Dynamin K44A Dynamin, Alanine44 Substituted With Lysine Dynamin, GTPase-Deficient Dynamin, Mutated Form, K44A GTPase Deficient Dynamin |
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