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Descriptor English: Motor Neuron Disease
Descriptor Spanish: Enfermedad de la Neurona Motora
Descriptor enfermedad de la neurona motora
Entry term(s) enfermedad de la motoneurona
enfermedad de la neurona motora familiar
enfermedad de la neurona motora inferior
enfermedad de la neurona motora superior
enfermedad de las células del asta anterior
esclerosis lateral
Scope note: Enfermedades caracterizadas por degeneración selectiva de las neuronas motoras de la médula espinal, tronco encefálico o corteza motora. Los subtipos clínicos se distinguen por el principal sitio de degeneración. En la ESCLEROSIS LATERAL AMIOTRÓFICA hay afectación de las neuronas motoras superiores, inferiores y del tronco encefálico. En la atrofia muscular progresiva y síndromes relaciondos (ver ATROFIA MUSCULAR ESPINAL) las neuronas motoras medulares son las principalmente afectadas. En la parálisis bulbar progresiva (PARÁLISIS BULBAR PROGRESIVA) la degeneración inicial se produce en el tronco encefálico. En la esclerosis lateral primaria, las neuronas corticales son las únicas afectadas. (Adams et al., Principles of Neurology, 6th ed, p1089)
Descriptor Portuguese: Doença dos Neurônios Motores
Descriptor French: Maladies du motoneurone
Entry term(s): Anterior Horn Cell Disease
Familial Motor Neuron Disease
Lateral Scleroses
Lateral Scleroses, Primary
Lateral Sclerosis
Lateral Sclerosis, Primary
Lower Motor Neuron Disease
Motor Neuron Disease, Familial
Motor Neuron Disease, Lower
Motor Neuron Disease, Secondary
Motor Neuron Disease, Upper
Motor Neuron Diseases
Motor System Disease
Motor System Diseases
Neuron Disease, Motor
Neuron Diseases, Motor
Primary Lateral Scleroses
Primary Lateral Sclerosis
Scleroses, Lateral
Scleroses, Primary Lateral
Sclerosis, Lateral
Sclerosis, Primary Lateral
Secondary Motor Neuron Disease
Upper Motor Neuron Disease
Tree number(s): C10.574.562
C10.668.467
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016472
Scope note: Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
Annotation: general or unspecified; prefer specifics
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Previous Indexing: Motor Neurons (1966-1991)
Neuromuscular Diseases (1972-1991)
Public MeSH Note: 92
History Note: 92
Entry Version: MOTOR NEURON DIS
DeCS ID: 29957
Unique ID: D016472
NLM Classification: WE 550
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1992/01/01
Date of Entry: 1991/06/21
Revision Date: 2010/06/25
Motor Neuron Disease - Preferred
Concept UI M0025158
Scope note Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
Preferred term Motor Neuron Disease
Entry term(s) Motor Neuron Diseases
Motor System Disease
Motor System Diseases
Neuron Disease, Motor
Neuron Diseases, Motor
Familial Motor Neuron Disease - Narrower
Concept UI M0337053
Preferred term Familial Motor Neuron Disease
Entry term(s) Motor Neuron Disease, Familial
Lateral Sclerosis - Narrower
Concept UI M0001057
Preferred term Lateral Sclerosis
Entry term(s) Lateral Scleroses
Lateral Scleroses, Primary
Lateral Sclerosis, Primary
Primary Lateral Scleroses
Primary Lateral Sclerosis
Scleroses, Lateral
Scleroses, Primary Lateral
Sclerosis, Lateral
Sclerosis, Primary Lateral
Motor Neuron Disease, Upper - Narrower
Concept UI M0337056
Preferred term Motor Neuron Disease, Upper
Entry term(s) Upper Motor Neuron Disease
Motor Neuron Disease, Secondary - Narrower
Concept UI M0337057
Preferred term Motor Neuron Disease, Secondary
Entry term(s) Secondary Motor Neuron Disease
Anterior Horn Cell Disease - Narrower
Concept UI M0337052
Preferred term Anterior Horn Cell Disease
Motor Neuron Disease, Lower - Narrower
Concept UI M0337054
Preferred term Motor Neuron Disease, Lower
Entry term(s) Lower Motor Neuron Disease



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