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Descriptor English: Interleukin-10
Descriptor Spanish: Interleucina-10
Descriptor interleucina-10
Entry term(s) IL-10
Scope note: Citocina producida por una variedad de tipos celulares, que incluyen LINFOCITOS T, MONOCITOS, CÉLULAS DENDRÍTICAS y CÉLULAS EPITELIALES que ejerce una variedad de efectos sobre la inmunorregulación e INFLAMACIÓN. La interleucina 10 se combina consigo misma para formar una molécula homodimérica que es biológicamente activa de la proteína.
Descriptor Portuguese: Interleucina-10
Descriptor French: Interleukine-10
Entry term(s): CSIF-10
Cytokine Synthesis Inhibitory Factor
IL-10
IL10
Interleukin 10
Tree number(s): D12.644.276.374.465.510
D12.776.467.374.465.510
D23.529.374.465.510
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016753
Scope note: A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and EPITHELIAL CELLS that exerts a variety of effects on immunoregulation and INFLAMMATION. Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 130068-27-8
CAS Type 1 Name: Cytokine formation-inhibiting factor (mouse clone F115 protein moiety reduced)
Previous Indexing: Interleukins (1990-1991)
Public MeSH Note: 92; INTERLEUKIN-10 (NM) was indexed under INTERLEUKINS 1990-91
Online Note: use INTERLEUKIN-10 (NM) to search INTERLEUKIN-10 1990-91
History Note: 92; was INTERLEUKIN-10 (NM) 1990-91
DeCS ID: 30030
Unique ID: D016753
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1992/01/01
Date of Entry: 1991/06/27
Revision Date: 2006/07/05
Interleukin-10 - Preferred
Concept UI M0025510
Scope note A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and EPITHELIAL CELLS that exerts a variety of effects on immunoregulation and INFLAMMATION. Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein.
Preferred term Interleukin-10
Entry term(s) CSIF-10
Cytokine Synthesis Inhibitory Factor
IL-10
IL10
Interleukin 10



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