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Descriptor English: Interleukin-23
Descriptor Spanish: Interleucina-23
Descriptor interleucina-23
Entry term(s) IL-23
Scope note: Citocina heterodimérica que desempeña un papel en las respuestas inmunitarias innatas y adaptativas. La interleucina 23 se compone de una subunidad de 19 kDa y una subunidad de 40kDa que es compartida por la INTERLEUCINA 12. Está producida por las CÉLULAS DENDRÍTICAS, MACRÓFAGOS y una variedad de otras células inmunitarias.
Descriptor Portuguese: Interleucina-23
Descriptor French: Interleukine-23
Entry term(s): IL-23
Interleukin 23
Tree number(s): D12.644.276.374.465.759
D12.776.467.374.465.759
D23.529.374.465.550
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053759
Scope note: A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-23 is comprised of a unique 19 kDa subunit and 40 kDa subunit that is shared with INTERLEUKIN-12. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Angiogenesis Inhibitors
Public MeSH Note: 2007; INTERLEUKIN-23 was indexed under INTERLEUKINS 2001-2006
History Note: 2007(2001)
Related: Ustekinumab MeSH
DeCS ID: 52280
Unique ID: D053759
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2017/04/14
Interleukin-23 - Preferred
Concept UI M0376076
Scope note A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-23 is comprised of a unique 19 kDa subunit and 40 kDa subunit that is shared with INTERLEUKIN-12. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells
Preferred term Interleukin-23
Entry term(s) IL-23
Interleukin 23



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