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Descriptor English: Interleukin-21
Descriptor Spanish: Interleucina-21
Descriptor Portuguese: Interleucina-21
Descriptor French: Without translation
Entry term(s): IL-21
IL21
Interleukin 21
Tree number(s): D12.644.276.374.465.027
D12.776.467.374.465.027
D23.529.374.465.162
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000098546
Scope note: INTERLEUKINS that affect the differentiation and function of LYMPHOCYTES and MYELOID CELLS and regulate both IMMUNITY, INNATE and ADAPTIVE IMMUNITY. They are also involved in the expansion of NK CELLS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Public MeSH Note: 2025; INTERLEUKIN-21 was indexed under INTERLEUKINS 2000-2024
History Note: 2025 (2000)
DeCS ID: 60854
Unique ID: D000098546
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2025/01/01
Date of Entry: 2024/08/09
Revision Date: 2024/08/06
Interleukin-21 - Preferred
Concept UI M0373673
Scope note INTERLEUKINS that affect the differentiation and function of LYMPHOCYTES and MYELOID CELLS and regulate both IMMUNITY, INNATE and ADAPTIVE IMMUNITY. They are also involved in the expansion of NK CELLS.
Preferred term Interleukin-21
Entry term(s) IL-21
IL21
Interleukin 21



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