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Descriptor English: Cyclic GMP
Descriptor Spanish: GMP Cíclico
Descriptor Portuguese: GMP Cíclico
Descriptor French: GMP cyclique
Entry term(s): 3',5'-Monophosphate, Guanosine Cyclic
Cyclic 3',5'-Monophosphate, Guanosine
Cyclic Monophosphate, Guanosine
Cyclic-3',5'-Monophosphate, Guanosine
GMP, Cyclic
Guanosine Cyclic 3',5' Monophosphate
Guanosine Cyclic 3',5'-Monophosphate
Guanosine Cyclic 3,5 Monophosphate
Guanosine Cyclic Monophosphate
Guanosine Cyclic-3',5'-Monophosphate
Monophosphate, Guanosine Cyclic
Tree number(s): D03.633.100.759.646.454.160
D13.695.462.275
D13.695.667.454.160
D13.695.827.426.160
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D006152
Scope note: Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: H2D2X058MU
CAS Type 1 Name: Guanosine, cyclic 3',5'-(hydrogen phosphate)
Previous Indexing: Guanine Nucleotides (1966-1971)
Public MeSH Note: 94; was GUANOSINE CYCLIC MONOPHOSPHATE 1980-93, was GUANOSINE CYCLIC-3',5'-MONOPHOSPHATE 1978-79, was GUANOSINE CYCLIC 3',5' MONOPHOSPHATE 1972-77; CYCLIC GMP was see GUANOSINE CYCLIC MONOPHOSPHATE 1975-93; GUANOSINE CYCLIC 2',3'-MONOPHOSPHATE was see GUANOSINE CYCLIC MONOPHOSPHATE 1980-93
Online Note: use CYCLIC GMP to search GUANOSINE CYCLIC MONOPHOSPHATE & GUANOSINE CYCLIC 2',3'-MONOPHOSPHATE 1980-93 & GUANOSINE CYCLIC-3',5'-MONOPHOSPHATE 1971-79 (as Prov 1971)
History Note: 94; was GUANOSINE CYCLIC MONOPHOSPHATE 1980-93, was GUANOSINE CYCLIC-3',5'-MONOPHOSPHATE 1978-79, was GUANOSINE CYCLIC 3',5' MONOPHOSPHATE 1971-77 (Prov 1971); CYCLIC GMP was see GUANOSINE CYCLIC MONOPHOSPHATE 1975-93; GUANOSINE CYCLIC 2',3'-MONOPHOSPHATE was see GUANOSINE CYCLIC MONOPHOSPHATE 1980-93
Entry Version: CYCL GMP
DeCS ID: 31736
Unique ID: D006152
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1972/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/28
Cyclic GMP - Preferred
Concept UI M0009685
Scope note Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
Preferred term Cyclic GMP
Entry term(s) 3',5'-Monophosphate, Guanosine Cyclic
Cyclic 3',5'-Monophosphate, Guanosine
Cyclic Monophosphate, Guanosine
Cyclic-3',5'-Monophosphate, Guanosine
GMP, Cyclic
Guanosine Cyclic 3',5' Monophosphate
Guanosine Cyclic 3',5'-Monophosphate
Guanosine Cyclic 3,5 Monophosphate
Guanosine Cyclic Monophosphate
Guanosine Cyclic-3',5'-Monophosphate
Monophosphate, Guanosine Cyclic



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