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Descriptor English: Guanosine Pentaphosphate
Descriptor Spanish: Guanosina Pentafosfato
Descriptor Portuguese: Guanosina Pentafosfato
Descriptor French: Guanosine pentaphosphate
Entry term(s): (p)ppGpp
3'-Diphosphate 5'-Triphosphate, Guanosine
5'-Triphosphate, Guanosine 3'-Diphosphate
Alarmone
Alarmone pppGpp
Bacterial Magic Spot pppGpp
Guanosine 3' Diphosphate 5' Triphosphate
Guanosine 3'-Diphosphate 5'-Triphosphate
Pentaphosphate, Guanosine
pppGpp, Alarmone
ppprGpp
Tree number(s): D03.633.100.759.646.454.440
D13.695.667.454.440
D13.695.827.426.440
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D006158
Scope note: Guanosine 5'-triphosphate 2'(3')-diphosphate. A guanine nucleotide containing five phosphate groups. Three phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position. This nucleotide serves as a messenger to turn off the synthesis of ribosomal RNA when amino acids are not available for protein synthesis.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 38918-96-6
CAS Type 1 Name: Guanosine 5'-(tetrahydrogen triphosphate), 3'-(trihydrogen diphosphate)
Previous Indexing: Guanine Nucleotides (1966-1977)
Public MeSH Note: 91; was see under GUANINE NUCLEOTIDES 1978-90
History Note: 91(78); was see under GUANINE NUCLEOTIDES 1978-90
Entry Version: PPPGPP
DeCS ID: 6308
Unique ID: D006158
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1977/04/22
Revision Date: 2020/02/28
Guanosine Pentaphosphate - Preferred
Concept UI M0009692
Scope note Guanosine 5'-triphosphate 2'(3')-diphosphate. A guanine nucleotide containing five phosphate groups. Three phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position. This nucleotide serves as a messenger to turn off the synthesis of ribosomal RNA when amino acids are not available for protein synthesis.
Preferred term Guanosine Pentaphosphate
Entry term(s) (p)ppGpp
3'-Diphosphate 5'-Triphosphate, Guanosine
5'-Triphosphate, Guanosine 3'-Diphosphate
Alarmone pppGpp
Bacterial Magic Spot pppGpp
Guanosine 3' Diphosphate 5' Triphosphate
Guanosine 3'-Diphosphate 5'-Triphosphate
Pentaphosphate, Guanosine
pppGpp, Alarmone
ppprGpp
Alarmone - Related but not broader or narrower
Concept UI M000679557
Preferred term Alarmone



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