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Descriptor English: ATP Binding Cassette Transporter, Subfamily B, Member 11
Descriptor Spanish: Miembro 11 de la Subfamilia B de Transportador de Casetes de Unión al ATP
Descriptor transportador de casetes de unión al ATP subfamilia B, miembro 11
Entry term(s) bomba de exportación de sales biliares
miembro 11 de la subfamilia B de casetes de unión al ATP
miembro 11 de la subfamilia B de transportadores de casetes de unión al ATP
proteína ABCB11
proteína BSEP
Scope note: Subfamilia B de proteínas transportadoras de casetes de unión a ATP (glucoproteínas P) que actúan en la secreción dependiente de ATP de las SALES BILIARES a los CANALÍCULOS BILIARES de los HEPATOCITOS. Las mutaciones del gen ABCB11 se asocian a colestasis intrahepática familiar progresiva 2 (ver COLESTASIS INTRAHEPÁTICA).
Descriptor Portuguese: Membro 11 da Subfamília B de Transportadores de Cassetes de Ligação de ATP
Descriptor French: Membre-11 de la sous-famille B à cassette liant l'ATP
Entry term(s): ABCB11 Protein
ATP Binding Cassette Subfamily B Member 11
ATP Binding Cassette Transporter, Sub-Family B, Member 11
BSEP Protein
Bile Salt Export Pump
Tree number(s): D12.776.157.530.100.075.125
D12.776.157.530.450.074.500.500.250.438
D12.776.395.550.020.400.534
D12.776.543.550.192.400.534
D12.776.543.585.100.200.438
D12.776.543.585.450.074.500.500.250.438
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000074020
Scope note: ATP-binding cassette, subfamily B, protein (P-glycoproteins) that functions in the ATP-dependent secretion of BILE SALTS into the BILE CANALICULI of HEPATOCYTES. Mutations in the ABCB11 gene are associated with progressive familial intrahepatic cholestasis 2 (see CHOLESTASIS, INTRAHEPATIC).
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: ATP-Binding Cassette Transporters (1995-2017)
Public MeSH Note: 2019; see ATP BINDING CASSETTE SUBFAMILY B MEMBER 11 2018
History Note: 2019 (2018)
DeCS ID: 57076
Unique ID: D000074020
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2018/06/20
ATP Binding Cassette Transporter, Subfamily B, Member 11 - Preferred
Concept UI M000625193
Scope note ATP-binding cassette, subfamily B, protein (P-glycoproteins) that functions in the ATP-dependent secretion of BILE SALTS into the BILE CANALICULI of HEPATOCYTES. Mutations in the ABCB11 gene are associated with progressive familial intrahepatic cholestasis 2 (see CHOLESTASIS, INTRAHEPATIC).
Preferred term ATP Binding Cassette Transporter, Subfamily B, Member 11
Entry term(s) ABCB11 Protein
ATP Binding Cassette Subfamily B Member 11
ATP Binding Cassette Transporter, Sub-Family B, Member 11
BSEP Protein
Bile Salt Export Pump



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