DeCS

Descriptor English:

ATP Binding Cassette Transporter, Subfamily B, Member 2

Descriptor Spanish:

Transportador de Casetes de Unión a ATP, Subfamilia B, Miembro 2

Spanish from Spain

Descriptor	transportador de casetes de unión al ATP, subfamilia B, miembro 2
Entry term(s)	ABCB2 RING4 casete de unión a ATP, subfamilia B, miembro 2 miembro 2 de la subfamilia B de casetes de unión al ATP proteína ABCB2 proteína RING4 proteína Really Interesting New Gene 4 proteína TAP 1 proteína TAP-1 proteína TAP1 transportador 1 asociado a la presentación de antígenos transportador 1 de casetes de unión de ATP de la subfamilia B (MDR-TAP) transportador TAP1 transportador de péptidos PSF1 transportador de péptidos TAP1
Scope note:	Proteína de la subfamilia B de casetes de unión a ATP (SUBFAMILIA B DE TRANSPORTADORES DE CASETES DE UNIÓN A ATP) que sirve para transportar ANTÍGENOS desde el CITOPLASMA hasta el RETÍCULO ENDOPLÁSMICO para su unión con los ANTÍGENOS DE HISTOCOMPATIBILIDAD CLASE I. También actúa como andamiaje molecular para el estadio final del PLEGAMIENTO DE PROTEÍNAS del CMH (Complejo Mayor de Histocompatibilidad) de clase I.

Descriptor Portuguese:

Membro 2 da Subfamília B de Transportadores de Cassetes de Ligação de ATP

Descriptor French:

Membre-2 de la sous-famille B à cassette de liaison à l'ATP

Entry term(s):

ABCB2 Protein
ATP Binding Cassette Sub Family B Member 2
ATP Binding Cassette Transporter, Sub-Family B, Member 2
ATP-Binding Cassette Sub-Family B Member 2
Antigen Peptide Transporter 1
Antigen Peptide Transporter-1
PSF1, Peptide Transporter
Peptide Transporter PSF1
Peptide Transporter TAP1
RING4 Protein
Really Interesting New Gene 4 Protein
TAP 1 Protein
TAP-1 Protein
TAP1 Protein
TAP1, Peptide Transporter
Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR-TAP)

Tree number(s):

D09.400.430.890.020.400.305
D12.776.157.530.100.075.250
D12.776.157.530.450.074.500.500.250.250
D12.776.395.550.020.400.305
D12.776.543.550.192.400.305
D12.776.543.585.100.200.250
D12.776.543.585.450.074.500.500.250.250

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D000071181

Scope note:

An ATP-binding cassette, sub-family B protein (ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B) that functions in the transport of ANTIGENS from the CYTOPLASM to the ENDOPLASMIC RETICULUM for association with HISTOCOMPATIBILITY ANTIGENS CLASS I peptides. It also acts as a molecular scaffold for the final stage of MHC class I PROTEIN FOLDING.

Allowable Qualifiers:

AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine

Concept UI	M000613424
Scope note	An ATP-binding cassette, sub-family B protein (ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B) that functions in the transport of ANTIGENS from the CYTOPLASM to the ENDOPLASMIC RETICULUM for association with HISTOCOMPATIBILITY ANTIGENS CLASS I peptides. It also acts as a molecular scaffold for the final stage of MHC class I PROTEIN FOLDING.
Preferred term	ATP Binding Cassette Transporter, Subfamily B, Member 2
Entry term(s)	ABCB2 Protein ATP Binding Cassette Sub Family B Member 2 ATP Binding Cassette Transporter, Sub-Family B, Member 2 ATP-Binding Cassette Sub-Family B Member 2 Antigen Peptide Transporter 1 Antigen Peptide Transporter-1 PSF1, Peptide Transporter Peptide Transporter PSF1 Peptide Transporter TAP1 RING4 Protein Really Interesting New Gene 4 Protein TAP 1 Protein TAP-1 Protein TAP1 Protein TAP1, Peptide Transporter Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR-TAP)

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