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Descriptor English: Neural Cell Adhesion Molecules
Descriptor Spanish: Moléculas de Adhesión de Célula Nerviosa
Descriptor moléculas de adhesión de células nerviosas
Entry term(s) MACN
NCAM
molécula de adhesión celular nerviosa
molécula de adhesión de células nerviosas
Scope note: Molécula de adhesión celular que participa en una diversa gama de interacciones mediadas por el contacto entre las neuronas, astrocitos, oligodendrocitos, y miotubos. Se expresa amplia pero transitoriamente en muchos tejidos en las primeras fases de la embriogénesis. Existen cuatro isoformas principales, incluido CD56 (ANTÍGENOS, CD56), pero hay otras muchas variantes que se producen por ayuste alternativo y modificaciones post-translacionales. (Pigott & Power, The Adhesion Molecule FactsBook, 1993, pp115-119)
Descriptor Portuguese: Moléculas de Adesão de Célula Nervosa
Descriptor French: Molécules d'adhérence cellulaire neurales
Entry term(s): Cell Adhesion Molecule, Neural
Cell Adhesion Molecules, Neural
NCAM
Neural Cell Adhesion Molecule
Tree number(s): D09.400.430.890.200.250.520
D12.776.395.550.200.250.520
D12.776.543.550.200.250.520
D23.050.301.350.250.520
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019006
Scope note: Cell adhesion molecule involved in a diverse range of contact-mediated interactions among neurons, astrocytes, oligodendrocytes, and myotubes. It is widely but transiently expressed in many tissues early in embryogenesis. Four main isoforms exist, including CD56; (CD56 ANTIGEN); but there are many other variants resulting from alternative splicing and post-translational modifications. (From Pigott & Power, The Adhesion Molecule FactsBook, 1993, pp115-119)
Annotation: NCAM: note entry term NEURAL CELL ADHESION MOLECULE but do not confuse this entry term with NEURONAL CELL ADHESION MOLECULES see CELL ADHESION MOLECULES, NEURONAL
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Cell Adhesion Molecules, Neuronal (1990-1995)
Public MeSH Note: 96
History Note: 96
DeCS ID: 32667
Unique ID: D019006
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1996/01/01
Date of Entry: 1995/05/26
Revision Date: 2017/07/13
Neural Cell Adhesion Molecules - Preferred
Concept UI M0028384
Scope note Cell adhesion molecule involved in a diverse range of contact-mediated interactions among neurons, astrocytes, oligodendrocytes, and myotubes. It is widely but transiently expressed in many tissues early in embryogenesis. Four main isoforms exist, including CD56; (CD56 ANTIGEN); but there are many other variants resulting from alternative splicing and post-translational modifications. (From Pigott & Power, The Adhesion Molecule FactsBook, 1993, pp115-119)
Preferred term Neural Cell Adhesion Molecules
Entry term(s) Cell Adhesion Molecule, Neural
Cell Adhesion Molecules, Neural
NCAM
Neural Cell Adhesion Molecule



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