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Descriptor English: Okadaic Acid
Descriptor Spanish: Ácido Ocadaico
Descriptor ácido ocadaico
Scope note: Inhibidor específico de la fosfoserina y treonina proteína fosfatasa 1 y 2a. Es también un potente promotor tumoral. Es producido por los DINOFLAGELADOS y causa INTOXICACIÓN POR MARISCO asociada a diarrea.
Descriptor Portuguese: Ácido Okadáico
Descriptor French: Acide okadaïque
Entry term(s): Acid, Ocadaic
Acid, Okadaic
Ocadaic Acid
Tree number(s): D02.355.291.705
D23.946.580.710
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019319
Scope note: A specific inhibitor of phosphoserine/threonine protein phosphatase 1 and 2a. It is also a potent tumor promoter. It is produced by DINOFLAGELLATES and causes diarrhetic SHELLFISH POISONING.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Carcinogens
Enzyme Inhibitors
Ionophores
Registry Number: 1W21G5Q4N2
Previous Indexing: Ethers, Cyclic (1982-1996)
Public MeSH Note: 97; OKADAIC ACID was indexed under ETHERS, CYCLIC 1982-96
Online Note: use OKADAIC ACID (NM) to search OKADAIC ACID 1982-96
History Note: 97; was OKADAIC ACID (NM) 1982-96
DeCS ID: 32984
Unique ID: D019319
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1997/01/01
Date of Entry: 1996/06/10
Revision Date: 2020/02/28
Okadaic Acid - Preferred
Concept UI M0028765
Scope note A specific inhibitor of phosphoserine/threonine protein phosphatase 1 and 2a. It is also a potent tumor promoter. It is produced by DINOFLAGELLATES and causes diarrhetic SHELLFISH POISONING.
Preferred term Okadaic Acid
Entry term(s) Acid, Ocadaic
Acid, Okadaic
Ocadaic Acid



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