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Descriptor English: Saxitoxin
Descriptor Spanish: Saxitoxina
Descriptor saxitoxina
Entry term(s) toxina gonyaulaxa
Scope note: Compuesto que contiene un anillo purínico reducido aunque no tiene relación biosintética con los alcaloides purínicos. Es un tóxico que en ocasiones está presente en ciertos moluscos comestibles; es elaborada por GONYAULAX y consumida por moluscos, pescados, etc. sin efectos nocivos. Es neurotóxico y produce PARÁLISIS RESPIRATORIA y otros efectos en los MAMÍFEROS, cuadro que se conoce como intoxicación paralítica por MOLLUSCA.
Descriptor Portuguese: Saxitoxina
Descriptor French: Saxitoxine
Entry term(s): Gonyaulax Toxin
Mitilotoxin
Saxitonin
Toxin, Gonyaulax
Tree number(s): D03.633.100.759.794
D20.888.590.662
D23.946.123.257.750
D23.946.580.590.662
D23.946.580.830
D23.946.833.590.662
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012530
Scope note: A compound that contains a reduced purine ring system but is not biosynthetically related to the purine alkaloids. It is a poison found in certain edible mollusks at certain times; elaborated by GONYAULAX and consumed by mollusks, fishes, etc. without ill effects. It is neurotoxic and causes RESPIRATORY PARALYSIS and other effects in MAMMALS, known as paralytic SHELLFISH poisoning.
Annotation: /antag permitted but consider also ANTITOXINS
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Poisons
Registry Number: 35523-89-8
CAS Type 1 Name: 1H,10H-Pyrrolo(1,2-c)purine-10,10-diol, 2,6-diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-, (3aS-(3aalpha,4alpha,10aR*))-
Public MeSH Note: 74
History Note: 74
DeCS ID: 12912
Unique ID: D012530
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Saxitoxin - Preferred
Concept UI M0019455
Scope note A compound that contains a reduced purine ring system but is not biosynthetically related to the purine alkaloids. It is a poison found in certain edible mollusks at certain times; elaborated by GONYAULAX and consumed by mollusks, fishes, etc. without ill effects. It is neurotoxic and causes RESPIRATORY PARALYSIS and other effects in MAMMALS, known as paralytic SHELLFISH poisoning.
Preferred term Saxitoxin
Entry term(s) Gonyaulax Toxin
Mitilotoxin
Saxitonin
Toxin, Gonyaulax



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