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Descriptor English: HIV Integrase
Descriptor Spanish: Integrasa de VIH
Descriptor integrasa del VIH
Entry term(s) VIH integrasa
Scope note: Enzima del VIRUS DE LA INMUNODEFICIENCIA HUMANA necesaria para integrar el ADN viral en el ADN celular, en el núcleo de una célula huésped. La integrasa del VIH es una nucleotidiltransferasa de ADN codificada por el gen pol.
Descriptor Portuguese: Integrase de HIV
Descriptor French: Intégrase du VIH
Entry term(s): HIV Integration Protein
Integrase, HIV
Integration Protein, HIV
p31 Integrase Protein, HIV
p31 Integrase Protein, Human Immunodeficiency Virus
p31 pol Gene Product, HIV
p31 pol Gene Product, Human Immunodeficiency Virus
Tree number(s): D08.811.739.500.667.500
D08.811.913.696.445.825.500
D12.776.964.775.375.545.500
D12.776.964.775.562.764.500
D12.776.964.900.750.500.545.500
D12.776.964.970.600.850.375.545.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019427
Scope note: Enzyme of the HUMAN IMMUNODEFICIENCY VIRUS that is required to integrate viral DNA into cellular DNA in the nucleus of a host cell. HIV integrase is a DNA nucleotidyltransferase encoded by the pol gene.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:HIV Integrase Inhibitors
Registry Number: EC 2.7.7.-
Previous Indexing: DNA Nucleotidyltransferases (1993-1996)
Public MeSH Note: 97; HIV INTEGRASE was indexed under DNA NUCLEOTIDYLTRANSFERASES 1993-96
Online Note: use INTEGRASE (NM) to search HIV INTEGRASE 1993-96
History Note: 97; HIV INTEGRASE was SY to INTEGRASE (NM) 1993-96
DeCS ID: 33024
Unique ID: D019427
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1997/01/01
Date of Entry: 1996/06/13
Revision Date: 2013/07/08
HIV Integrase - Preferred
Concept UI M0028901
Scope note Enzyme of the HUMAN IMMUNODEFICIENCY VIRUS that is required to integrate viral DNA into cellular DNA in the nucleus of a host cell. HIV integrase is a DNA nucleotidyltransferase encoded by the pol gene.
Preferred term HIV Integrase
Entry term(s) HIV Integration Protein
Integrase, HIV
Integration Protein, HIV
p31 Integrase Protein, HIV
p31 Integrase Protein, Human Immunodeficiency Virus
p31 pol Gene Product, HIV
p31 pol Gene Product, Human Immunodeficiency Virus



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