Descriptor English: | Topotecan |
Descriptor Spanish: | Topotecan |
Descriptor Portuguese: | Topotecan |
Descriptor French: | Topotécane |
Entry term(s): |
9 Dimethylaminomethyl 10 hydroxycamptothecin 9-Dimethylaminomethyl-10-hydroxycamptothecin Hycamtamine Hycamtin Hydrochloride, Nogitecan Hydrochloride, Topotecan NSC 609699 NSC-609699 NSC609699 Nogitecan Hydrochloride SK&F 104864 A SK&F-104864-A SK&F104864A SKF 104864 A SKF-104864-A SKF104864A Topotecan Hydrochloride Topotecan Monohydrochloride, (S)-Isomer |
Tree number(s): |
D03.132.151.850 |
RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D019772 |
Scope note: | An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I. |
Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
Pharm Action: |
Topoisomerase I Inhibitors |
Registry Number: | 7M7YKX2N15 |
Previous Indexing: |
Camptothecin/analogs & derivatives (1991-1997) |
Public MeSH Note: | 98; TOPOTECAN was indexed under CAMPTOTHECIN/analogs & derivatives 1991-97 |
History Note: | 98; use TOPOTECAN (NM) 1991-97 |
DeCS ID: | 33404 |
Unique ID: | D019772 |
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents |
Date Established: | 1998/01/01 |
Date of Entry: | 1997/06/20 |
Revision Date: | 2017/01/17 |
Topotecan
- Preferred
Topotecan Hydrochloride
- Narrower
SK&F-104864-A
- Narrower
Hycamtin
- Narrower
NSC-609699
- Narrower
Hycamtamine
- Narrower
Concept UI |
M0029340 |
Scope note | An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I. |
Preferred term | Topotecan |
Entry term(s) |
9 Dimethylaminomethyl 10 hydroxycamptothecin 9-Dimethylaminomethyl-10-hydroxycamptothecin |
Concept UI |
M0329084 |
Preferred term | Topotecan Hydrochloride |
Entry term(s) |
Hydrochloride, Nogitecan Hydrochloride, Topotecan Nogitecan Hydrochloride Topotecan Monohydrochloride, (S)-Isomer |
Concept UI |
M0352761 |
Preferred term | SK&F-104864-A |
Entry term(s) |
SK&F 104864 A SK&F104864A SKF 104864 A SKF-104864-A SKF104864A |
Concept UI |
M0352657 |
Preferred term | Hycamtin |
Concept UI |
M0352658 |
Preferred term | NSC-609699 |
Entry term(s) |
NSC 609699 NSC609699 |
Concept UI |
M000623496 |
Preferred term | Hycamtamine |
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