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Descriptor English: Troponin T
Descriptor Spanish: Troponina T
Descriptor troponina T
Scope note: Subunidad del complejo de la TROPONINA que se une a la TROPOMIOSINA. Existen tres subtipos: la troponina T2, que es específica del corazón, y las troponinas T1 y T3, que son esqueléticas. La troponina T2 es un BIOMARCADOR de daño en los MIOCITOS CARDÍACOS. Las mutaciones en el gen de la troponina T2 se asocian a la MIOCARDIOPATÍA HIPERTRÓFICA FAMILIAR.
Descriptor Portuguese: Troponina T
Descriptor French: Troponine T
Entry term(s): Troponin T1
Troponin T2
Troponin T3
Troponin-T
Tree number(s): D05.500.945.962
D05.750.078.730.825.962
D12.776.210.500.910.962
D12.776.220.525.825.962
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020107
Scope note: A TROPONIN complex subunit that binds to TROPOMYOSIN. There are three troponin T subtypes: troponin T1, T2 and T3. Troponin T2 is cardiac-specific whereas troponin T2 and T3 are skeletal subtypes. Troponin T2 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin T2 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
Annotation: TROPONIN C & TROPONIN I are also available
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Troponin (1981-1998)
Public MeSH Note: 99; TROPONIN T was indexed under TROPONIN 1981-98
History Note: 99; use TROPONIN T (NM) 1981-98
Related: Cardiomyopathy, Hypertrophic, Familial MeSH
DeCS ID: 33838
Unique ID: D020107
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1999/01/01
Date of Entry: 1998/06/11
Revision Date: 2016/07/01
Troponin T - Preferred
Concept UI M0029843
Scope note A TROPONIN complex subunit that binds to TROPOMYOSIN. There are three troponin T subtypes: troponin T1, T2 and T3. Troponin T2 is cardiac-specific whereas troponin T2 and T3 are skeletal subtypes. Troponin T2 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin T2 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
Preferred term Troponin T
Entry term(s) Troponin-T
Troponin T1 - Narrower
Concept UI M0029845
Preferred term Troponin T1
Troponin T2 - Narrower
Concept UI M0029844
Preferred term Troponin T2
Troponin T3 - Narrower
Concept UI M000617982
Preferred term Troponin T3



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