| Descriptor English: | Interleukin-18 | ||||||
| Descriptor Spanish: |
Interleucina-18
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| Descriptor Portuguese: | Interleucina-18 | ||||||
| Descriptor French: | Interleukine-18 | ||||||
| Entry term(s): |
IFN gamma Inducing Factor IFN-gamma Inducing Factor IFN-gamma-Inducing Factor IL-18 IL18 Inducing Factor, IFN-gamma Inducing Factor, Interferon-gamma Interferon gamma Inducing Factor Interferon-gamma Inducing Factor Interferon-gamma-Inducing Factor Interleukin 18 |
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| Tree number(s): |
D12.644.276.374.465.518 D12.776.467.374.465.518 D23.529.374.465.518 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D020382 | ||||||
| Scope note: | A cytokine which resembles IL-1 structurally and IL-12 functionally. It enhances the cytotoxic activity of NK CELLS and CYTOTOXIC T-LYMPHOCYTES, and appears to play a role both as neuroimmunomodulator and in the induction of mucosal immunity. |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Previous Indexing: |
Cytokines (1995-1998) |
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| Public MeSH Note: | 99; INTERFERON-GAMMA INDUCING FACTOR (now INTERLEUKIN-18) was indexed under CYTOKINES 1995-98 |
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| History Note: | 99; use INTERLEUKIN-18 (NM) 1995-98 |
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| DeCS ID: | 33854 | ||||||
| Unique ID: | D020382 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1999/01/01 | ||||||
| Date of Entry: | 1998/06/10 | ||||||
| Revision Date: | 2006/07/05 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Interleukin-18
- Preferred
| Concept UI |
M0030026 |
| Scope note | A cytokine which resembles IL-1 structurally and IL-12 functionally. It enhances the cytotoxic activity of NK CELLS and CYTOTOXIC T-LYMPHOCYTES, and appears to play a role both as neuroimmunomodulator and in the induction of mucosal immunity. |
| Preferred term | Interleukin-18 |
| Entry term(s) |
IFN gamma Inducing Factor IFN-gamma Inducing Factor IFN-gamma-Inducing Factor IL-18 IL18 Inducing Factor, IFN-gamma Inducing Factor, Interferon-gamma Interferon gamma Inducing Factor Interferon-gamma Inducing Factor Interferon-gamma-Inducing Factor Interleukin 18 |
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