ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT Investigative Techniques [E05] Investigative Techniques Chemistry Techniques, Analytical [E05.196] Chemistry Techniques, Analytical Activation Analysis [E05.196.039] Activation Analysis Analytic Sample Preparation Methods [E05.196.059] Analytic Sample Preparation Methods Binding, Competitive [E05.196.080] Binding, Competitive Biuret Reaction [E05.196.085] Biuret Reaction Calorimetry [E05.196.131] Calorimetry Chemical Precipitation [E05.196.150] Chemical Precipitation Chemical Fractionation [E05.196.155] Chemical Fractionation Chemometrics [E05.196.168] Chemometrics Chromatography [E05.196.181] Chromatography Countercurrent Distribution [E05.196.278] Countercurrent Distribution Crystallization [E05.196.300] Crystallization Crystallography [E05.196.309] Crystallography Desiccation [E05.196.335] Desiccation Deuterium Exchange Measurement [E05.196.344] Deuterium Exchange Measurement Dialysis [E05.196.353] Dialysis Differential Thermal Analysis [E05.196.370] Differential Thermal Analysis Electroosmosis [E05.196.385] Electroosmosis Electrophoresis [E05.196.401] Electrophoresis Enzyme Assays [E05.196.427] Enzyme Assays Filtration [E05.196.454] Filtration Flow Injection Analysis [E05.196.460] Flow Injection Analysis Glucose Clamp Technique [E05.196.500] Glucose Clamp Technique Mass Spectrometry [E05.196.566] Mass Spectrometry Microchemistry [E05.196.620] Microchemistry Molecular Imprinting [E05.196.655] Molecular Imprinting Nucleotide Mapping [E05.196.680] Nucleotide Mapping Osmometry [E05.196.690] Osmometry Peptide Mapping [E05.196.700] Peptide Mapping Photometry [E05.196.712] Photometry Polarography [E05.196.749] Polarography Quartz Crystal Microbalance Techniques [E05.196.778] Quartz Crystal Microbalance Techniques Refractometry [E05.196.808] Refractometry Scattering, Radiation [E05.196.822] Scattering, Radiation Spectrum Analysis [E05.196.867] Spectrum Analysis Spin Trapping [E05.196.885] Spin Trapping Surface Plasmon Resonance [E05.196.890] Surface Plasmon Resonance Thermogravimetry [E05.196.904] Thermogravimetry Titrimetry [E05.196.922] Titrimetry Ultracentrifugation [E05.196.941] Ultracentrifugation ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT Investigative Techniques [E05] Investigative Techniques Molecular Probe Techniques [E05.601] Molecular Probe Techniques Biosensing Techniques [E05.601.043] Biosensing Techniques Surface Plasmon Resonance [E05.601.043.700] Surface Plasmon Resonance

Surface Plasmon Resonance - Preferred

Concept UI	M0029983
Scope note	A biosensing technique in which biomolecules capable of binding to specific analytes or ligands are first immobilized on one side of a metallic film. Light is then focused on the opposite side of the film to excite the surface plasmons, that is, the oscillations of free electrons propagating along the film's surface. The refractive index of light reflecting off this surface is measured. When the immobilized biomolecules are bound by their ligands, an alteration in surface plasmons on the opposite side of the film is created which is directly proportional to the change in bound, or adsorbed, mass. Binding is measured by changes in the refractive index. The technique is used to study biomolecular interactions, such as antigen-antibody binding.
Preferred term	Surface Plasmon Resonance
Entry term(s)	Plasmon Resonance, Surface Plasmon Resonances, Surface Resonance, Surface Plasmon Resonances, Surface Plasmon Surface Plasmon Resonances