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Descriptor English: Surface Plasmon Resonance
Descriptor Spanish: Resonancia por Plasmón de Superficie
Descriptor resonancia de plasmones de superficie
Scope note: Técnica biosensora en que las biomoléculas capaces de enlazar con analitos o enlaces específicos son primero inmovilizadas en una cara de una película metálica. Entonces se proyecta luz por la cara opuesta de la película, para excitar los plasmones de superficie, o sea, las oscilaciones de los electrones libres propagándose a lo largo de la superficie de la película. Se mide el índice refractario de la luz que esta superficie refleja. Cuando las biomoléculas inmovilizadas son enlazadas por sus ligandos, se crea una alteración en los plasmones de superficie en la cara opuesta de la película, que es directamente proporcional al cambio en la masa enlazada o adsorbida. El enlace se mide por los cambios en el índice de refracción. La técnica se usa para estudiar las interacciones biomoleculares, como el enlace antígeno-anticuerpo.
Descriptor Portuguese: Ressonância de Plasmônio de Superfície
Descriptor French: Résonance plasmonique de surface
Entry term(s): Plasmon Resonance, Surface
Plasmon Resonances, Surface
Resonance, Surface Plasmon
Resonances, Surface Plasmon
Surface Plasmon Resonances
Tree number(s): E05.196.890
E05.601.043.700
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020349
Scope note: A biosensing technique in which biomolecules capable of binding to specific analytes or ligands are first immobilized on one side of a metallic film. Light is then focused on the opposite side of the film to excite the surface plasmons, that is, the oscillations of free electrons propagating along the film's surface. The refractive index of light reflecting off this surface is measured. When the immobilized biomolecules are bound by their ligands, an alteration in surface plasmons on the opposite side of the film is created which is directly proportional to the change in bound, or adsorbed, mass. Binding is measured by changes in the refractive index. The technique is used to study biomolecular interactions, such as antigen-antibody binding.
Annotation: do not confuse with plasmon, extrachromosomal genetic material
Allowable Qualifiers: CL classification
EC economics
ES ethics
HI history
IS instrumentation
MT methods
SN statistics & numerical data
ST standards
TD trends
VE veterinary
Previous Indexing: Biosensing Techniques (1991-1998)
Public MeSH Note: 99
History Note: 99
DeCS ID: 33868
Unique ID: D020349
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1999/01/01
Date of Entry: 1998/06/11
Revision Date: 2015/06/23
Surface Plasmon Resonance - Preferred
Concept UI M0029983
Scope note A biosensing technique in which biomolecules capable of binding to specific analytes or ligands are first immobilized on one side of a metallic film. Light is then focused on the opposite side of the film to excite the surface plasmons, that is, the oscillations of free electrons propagating along the film's surface. The refractive index of light reflecting off this surface is measured. When the immobilized biomolecules are bound by their ligands, an alteration in surface plasmons on the opposite side of the film is created which is directly proportional to the change in bound, or adsorbed, mass. Binding is measured by changes in the refractive index. The technique is used to study biomolecular interactions, such as antigen-antibody binding.
Preferred term Surface Plasmon Resonance
Entry term(s) Plasmon Resonance, Surface
Plasmon Resonances, Surface
Resonance, Surface Plasmon
Resonances, Surface Plasmon
Surface Plasmon Resonances



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