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Descriptor English: Paraneoplastic Cerebellar Degeneration
Descriptor Spanish: Degeneración Cerebelosa Paraneoplásica
Descriptor degeneración cerebelosa paraneoplásica
Entry term(s) degeneración cerebelosa paraneoplásica asociada a anti Yo
degeneración cerebelosa paraneoplásica asociada a anti-Yo
Scope note: Degeneración cerebelosa asociada con una neoplasia remota. Las manifestaciones clínicas son ataxia progresiva de los miembros, ATAXIA DE LA MARCHA, DISARTRIA y NISTAGMO. Histológicamente las neoplasias asociadas son generalmente carcinomas o linfomas. Patológicamente la corteza cerebelosa y los núcleos subcorticales muestran cambios degenerativos difusos. Se encuentran anticuerpos anti células de Purkinje en el suero (anti-Yo) aproximadamente en el 50 por ciento de los individuos afectados. (Adams et al., Principles of Neurology, 6th ed, p686)
Descriptor Portuguese: Degeneração Paraneoplásica Cerebelar
Descriptor French: Dégénérescence cérébelleuse paranéoplasique
Entry term(s): Anti Yo Associated Paraneoplastic Cerebellar Degeneration
Anti-Yo-Associated Paraneoplastic Cerebellar Degeneration
Cerebellar Degeneration, Paraneoplastic
Cerebellar Syndrome, Paraneoplastic
Cerebellar Syndromes, Paraneoplastic
Degeneration, Paraneoplastic Cerebellar
Paraneoplastic Cerebellar Degeneration, Anti Yo Associated
Paraneoplastic Cerebellar Degeneration, Anti-Yo-Associated
Paraneoplastic Cerebellar Syndrome
Paraneoplastic Cerebellar Syndromes
Tree number(s): C04.588.614.550.650
C04.730.856.650
C10.228.140.252.620
C10.574.781.700
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020362
Scope note: Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)
Annotation: coord with precoord organ/neopl term + histol type
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Previous Indexing: Cerebellar Ataxia (1975-1999)
Paraneoplastic Syndromes (1980-1999)
Public MeSH Note: 2000
History Note: 2000
Entry Version: PARANEOPL CEREBELLAR DEGENERATION
DeCS ID: 34185
Unique ID: D020362
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2000/01/01
Date of Entry: 1999/11/04
Revision Date: 2009/07/06
Paraneoplastic Cerebellar Degeneration - Preferred
Concept UI M0328227
Scope note Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)
Preferred term Paraneoplastic Cerebellar Degeneration
Entry term(s) Cerebellar Degeneration, Paraneoplastic
Cerebellar Syndrome, Paraneoplastic
Cerebellar Syndromes, Paraneoplastic
Degeneration, Paraneoplastic Cerebellar
Paraneoplastic Cerebellar Syndrome
Paraneoplastic Cerebellar Syndromes
Paraneoplastic Cerebellar Degeneration, Anti-Yo-Associated - Narrower
Concept UI M0335813
Preferred term Paraneoplastic Cerebellar Degeneration, Anti-Yo-Associated
Entry term(s) Anti Yo Associated Paraneoplastic Cerebellar Degeneration
Anti-Yo-Associated Paraneoplastic Cerebellar Degeneration
Paraneoplastic Cerebellar Degeneration, Anti Yo Associated



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