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Descriptor English: Neuregulins
Descriptor Spanish: Neurregulinas
Descriptor neurregulinas
Entry term(s) neurregulina
proteínas NRG
Scope note: Familia de péptidos encontrados originalmente como factores que estimulan la fosforilación del receptor erbB-2 (RECEPTORES ERBB-2). Se dan múltiples formas de NEURREGULINAS debido a corte y empalme alternativo de sus ARN mensajeros. Las NEURREGULINAS incluyen productos procedentes de tres genes conocidos (NGR1, NGR2 y NGR3).
Descriptor Portuguese: Neurregulinas
Descriptor French: Neurégulines
Entry term(s): NRG Proteins
Neuregulin
Neuronal Differentiation Factor, Cholinergic
Tree number(s): D12.644.276.860.550
D12.776.467.860.550
D12.776.631.600.550
D23.529.850.550
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020880
Scope note: A family of peptides originally found as factors that stimulate the phosphorylation of the erbB-2 receptor (RECEPTORS, ERBB-2). Multiple variant forms of NEUREGULINS occur due to alternative splicing of their mRNAs. The NEUREGULINS include products from the three known genes (NGR1; NGR2 and NGR3).
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Glycoproteins (1986-1999)
Public MeSH Note: 2000; NEURONAL DIFFERENTIATION FACTOR, CHOLINERGIC (now NEUREGULINS) was indexed under GLYCOPROTEINS 1986-1999
History Note: 2000; use NEUREGULINS (NM) 1986-1999
Related: Receptor, ErbB-2 MeSH
DeCS ID: 34464
Unique ID: D020880
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2000/01/01
Date of Entry: 1999/11/04
Revision Date: 2020/05/27
Neuregulins - Preferred
Concept UI M0328213
Scope note A family of peptides originally found as factors that stimulate the phosphorylation of the erbB-2 receptor (RECEPTORS, ERBB-2). Multiple variant forms of NEUREGULINS occur due to alternative splicing of their mRNAs. The NEUREGULINS include products from the three known genes (NGR1; NGR2 and NGR3).
Preferred term Neuregulins
Entry term(s) NRG Proteins
Neuregulin
Neuronal Differentiation Factor, Cholinergic - Narrower
Concept UI M0137315
Preferred term Neuronal Differentiation Factor, Cholinergic



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