| Descriptor English: | Guanine Nucleotide-Releasing Factor 2 | ||||||
| Descriptor Spanish: |
Factor 2 Liberador de Guanina Nucleótido
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| Descriptor Portuguese: | Fator 2 de Liberação do Nucleotídeo Guanina | ||||||
| Descriptor French: | Facteur-2 de libération de nucléotides guanyliques | ||||||
| Entry term(s): |
C3G Protein GRF 2 GRF-2 GRF2 GRF2 Protein GRF2 Protein, Mammalian Guanine Nucleotide Exchange Factor C3G RAP1GRF1 |
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| Tree number(s): |
D12.644.360.325.300.300 D12.776.476.325.300.300 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D020735 | ||||||
| Scope note: | A 145-kDa guanine nucleotide exchange factor that is specific for rap1 and ras GTP-BINDING PROTEINS. It associates with SH3 domains of the crk family of signaling proteins. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Proteins (1997-1999) |
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| Public MeSH Note: | 2000; GRF2 PROTEIN, MAMMALIAN was indexed under PROTEINS 1995-1999; C3G PROTEIN was indexed under PROTEINS 1997-1999 |
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| History Note: | 2000; use GUANINE NUCLEOTIDE EXCHANGE FACTORS (NM) 1997-1999 |
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| DeCS ID: | 34491 | ||||||
| Unique ID: | D020735 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2000/01/01 | ||||||
| Date of Entry: | 1999/11/03 | ||||||
| Revision Date: | 2015/11/23 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Guanine Nucleotide-Releasing Factor 2
- Preferred
| Concept UI |
M0328202 |
| Scope note | A 145-kDa guanine nucleotide exchange factor that is specific for rap1 and ras GTP-BINDING PROTEINS. It associates with SH3 domains of the crk family of signaling proteins. |
| Preferred term | Guanine Nucleotide-Releasing Factor 2 |
| Entry term(s) |
C3G Protein GRF 2 GRF-2 GRF2 GRF2 Protein GRF2 Protein, Mammalian Guanine Nucleotide Exchange Factor C3G RAP1GRF1 |
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