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Descriptor English: Phosphofructokinase-1, Liver Type
Descriptor Spanish: Fosfofructoquinasa-1 Tipo Hepático
Descriptor fosfofructocinasa-1 tipo hepático
Entry term(s) 6-fosfofructocinasa de tipo hepático
6-fosfofructoquinasa de tipo hepático
fosfofructoquinasa-1 de tipo hepático
Scope note: Enzima alostérica que regula la glicólisis por catalización de la transferencia de un grupo fosfato del ATP a fructosa-6-fosfato, dando lugar a fructosa-1-6-bifosfato. La 6-fosfofructosa-1-cinasa se localiza en el hígado humano como homotetrámero de subunidades L.
Descriptor Portuguese: Fosfofrutoquinase-1 Hepática
Descriptor French: Phosphofructokinase-1, liver type
Entry term(s): 6-Phosphofructokinase, Liver Type
Phosphofructo-1-kinase Isozyme B
Phosphofructokinase 1, Liver Type
Tree number(s): D08.811.913.696.620.225.850.500.249
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D025501
Scope note: An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In human liver, the 6-phosphofructose-1-kinase exists as the homotetramer of L subunits.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.1.-
Previous Indexing: 6-Phosphofructokinase (1977-2001)
Public MeSH Note: 2002
History Note: 2002
DeCS ID: 36113
Unique ID: D025501
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2004/07/13
Phosphofructokinase-1, Liver Type - Preferred
Concept UI M0374830
Scope note An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In human liver, the 6-phosphofructose-1-kinase exists as the homotetramer of L subunits.
Preferred term Phosphofructokinase-1, Liver Type
Entry term(s) 6-Phosphofructokinase, Liver Type
Phosphofructo-1-kinase Isozyme B
Phosphofructokinase 1, Liver Type



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