Descriptor English: | Phosphofructokinase-1, Type C | ||||||
Descriptor Spanish: |
Fosfofructoquinasa-1 Tipo C
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Descriptor Portuguese: | Fosfofrutoquinase-1 Tipo C | ||||||
Descriptor French: | Phosphofructokinase-1, type C | ||||||
Entry term(s): |
6-Phosphofructokinase, Platelet Type Phosphofructo-1-kinase Isozyme C Phosphofructokinase 1, Type C |
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Tree number(s): |
D08.811.913.696.620.225.850.500.750 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D025502 | ||||||
Scope note: | An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In the humans, 6-phosphofructose-1-kinase isozyme C is found in platelets, brain, heart, kidney, colon and testis. This isozyme C can exist as the homotetramer of C subunits (P subunits), or heterotetramer of C type and L type subunits. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Registry Number: | EC 2.7.1.- | ||||||
Previous Indexing: |
6-Phosphofructokinase (1977-2001) |
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Public MeSH Note: | 2002 |
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History Note: | 2002 |
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DeCS ID: | 36115 | ||||||
Unique ID: | D025502 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2002/01/01 | ||||||
Date of Entry: | 2001/07/25 | ||||||
Revision Date: | 2003/07/09 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Phosphofructokinase-1, Type C
- Preferred
Concept UI |
M0374833 |
Scope note | An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In the humans, 6-phosphofructose-1-kinase isozyme C is found in platelets, brain, heart, kidney, colon and testis. This isozyme C can exist as the homotetramer of C subunits (P subunits), or heterotetramer of C type and L type subunits. |
Preferred term | Phosphofructokinase-1, Type C |
Entry term(s) |
6-Phosphofructokinase, Platelet Type Phosphofructo-1-kinase Isozyme C Phosphofructokinase 1, Type C |
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