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Descriptor English: Phosphofructokinase-1, Type C
Descriptor Spanish: Fosfofructoquinasa-1 Tipo C
Descriptor fosfofructocinasa-1 tipo C
Entry term(s) 6-fosfofructocinasa tipo plaquetario
6-fosfofructocinasa-1 de tipo plaquetario
fosfofructocinasa-1 de tipo C
fosfofructoquinasa-1 tipo C
Scope note: Enzima alostérica que regula la glucólisis, catalizando la transferencia de un grupo fosfato del ATP a fructosa-6-fosfato para producir fructosa-1,6-bifosfato. En humanos, la fosfofructofructosa-1, isoenzima C se localiza en las plaquetas, el cerebro, corazón, riñón, colon y testículo. Esta isoenzima C puede ocurrir como homotetrámero de subunidades C o como heterotetrámero de sububidades C y L.
Descriptor Portuguese: Fosfofrutoquinase-1 Tipo C
Descriptor French: Phosphofructokinase-1, type C
Entry term(s): 6-Phosphofructokinase, Platelet Type
Phosphofructo-1-kinase Isozyme C
Phosphofructokinase 1, Type C
Tree number(s): D08.811.913.696.620.225.850.500.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D025502
Scope note: An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In the humans, 6-phosphofructose-1-kinase isozyme C is found in platelets, brain, heart, kidney, colon and testis. This isozyme C can exist as the homotetramer of C subunits (P subunits), or heterotetramer of C type and L type subunits.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.1.-
Previous Indexing: 6-Phosphofructokinase (1977-2001)
Public MeSH Note: 2002
History Note: 2002
DeCS ID: 36115
Unique ID: D025502
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2003/07/09
Phosphofructokinase-1, Type C - Preferred
Concept UI M0374833
Scope note An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In the humans, 6-phosphofructose-1-kinase isozyme C is found in platelets, brain, heart, kidney, colon and testis. This isozyme C can exist as the homotetramer of C subunits (P subunits), or heterotetramer of C type and L type subunits.
Preferred term Phosphofructokinase-1, Type C
Entry term(s) 6-Phosphofructokinase, Platelet Type
Phosphofructo-1-kinase Isozyme C
Phosphofructokinase 1, Type C



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