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Descriptor English: Phosphofructokinase-1, Muscle Type
Descriptor Spanish: Fosfofructoquinasa-1 Tipo Muscular
Descriptor fosfofructocinasa-1 tipo muscular
Entry term(s) 6-fosfofructocinasa de tipo muscular
6-fosfofructoquinasa de tipo muscular
fosfofructoquinasa-1 de tipo muscular
Scope note: Enzima alostérica que regula la glicólisis, catalizando la transferencia de un grupo fosfato del ATP a fructosa-6-fosfato para producir fructosa-1,6-bifosfato. En humanos, la FOSFOFRUCTOCINASA-1 de los músculos existe como homotretámero de subunidades M. Los defectos en esta enzima muscular causan la ENFERMEDAD POR ALMACENAMIENTO DE GLUCÓGENO TIPO I, también conocida como enfermedad de Tarui.
Descriptor Portuguese: Fosfofrutoquinase-1 Muscular
Descriptor French: Phosphofructokinase-1, muscle type
Entry term(s): 6-Phosphofructokinase, Muscle Type
Phosphofructo-1-kinase Isozyme A
Phosphofructokinase 1, Muscle Type
Tree number(s): D08.811.913.696.620.225.850.500.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D025203
Scope note: An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In humans, PHOSPHOFRUCTOKINASE-1 in muscle exists as the homotetramer of M subunits. Defects in this muscle enzyme cause GLYCOGEN STORAGE DISEASE TYPE VII, also known as Tarui's disease.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: deficiency:Glycogen Storage Disease Type VII
Registry Number: EC 2.7.1.-
Previous Indexing: 6-Phosphofructokinase (1977-2001)
Public MeSH Note: 2002
History Note: 2002
DeCS ID: 36114
Unique ID: D025203
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2005/07/25
Phosphofructokinase-1, Muscle Type - Preferred
Concept UI M0373928
Scope note An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In humans, PHOSPHOFRUCTOKINASE-1 in muscle exists as the homotetramer of M subunits. Defects in this muscle enzyme cause GLYCOGEN STORAGE DISEASE TYPE VII, also known as Tarui's disease.
Preferred term Phosphofructokinase-1, Muscle Type
Entry term(s) 6-Phosphofructokinase, Muscle Type
Phosphofructo-1-kinase Isozyme A
Phosphofructokinase 1, Muscle Type



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