Search
Descriptor English: Vascular Endothelial Growth Factor Receptor-1
Descriptor Spanish: Receptor 1 de Factores de Crecimiento Endotelial Vascular
Descriptor receptor 1 de factores de crecimiento endotelial vascular
Entry term(s) VEGFR-1
Scope note: Receptor del VEGF de 180 kD que se encuentra principalmente en las células endoteliales y es esencial para la vasculogénesis y el mantenimiento vascular. Es conocido también como Flt-1 (receptor tirosina cinasa 1 tipo fms). Una isoforma soluble del receptor ayustada alternativamente puede servir como proteína de unión que regula la disponibilidad de diversos ligandos para la unión del receptor del VEGF y la transducción de señales.
Descriptor Portuguese: Receptor 1 de Fatores de Crescimento do Endotélio Vascular
Descriptor French: Récepteur-1 au facteur croissance endothéliale vasculaire
Entry term(s): FLT VEGF Receptor
FLT1 RTK
FLT1 Receptor Tyrosine Kinase
Proto Oncogene Protein flt
Proto-Oncogene Protein flt
Receptor, FLT VEGF
Tyrosine Kinase, fms-Like
VEGF Receptor flt 1 Protein
VEGF Receptor flt-1 Protein
VEGF Receptor, FLT
VEGFR-1
Vascular Endothelial Growth Factor Receptor 1
fms-Like Tyrosine Kinase
Tree number(s): D08.811.913.696.620.682.725.400.950.100
D12.776.476.568.400.950.100
D12.776.543.750.630.750.100
D12.776.543.750.750.400.910.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D040281
Scope note: A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.10.1
Previous Indexing: Proto-Oncogene Proteins (1991-2002)
Receptor Protein-Tyrosine Kinases (1991-2002)
Receptors, Growth Factor (1993-2002)
Public MeSH Note: 2003; PROTO-ONCOGENE PROTEIN FLT (now VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1) was indexed under PROTO-ONCOGENE PROTEINS & RECEPTOR PROTEIN-TYROSINE KINASE 1991-2002
History Note: 2003; use VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1 (NM) 1990-2002; for FLK-1 RECEPTOR TYROSINE KINASE use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR (NM) 1993-2002
Entry Version: VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPT 1
DeCS ID: 37358
Unique ID: D040281
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2016/05/31
Vascular Endothelial Growth Factor Receptor-1 - Preferred
Concept UI M0175703
Scope note A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction.
Preferred term Vascular Endothelial Growth Factor Receptor-1
Entry term(s) FLT VEGF Receptor
FLT1 RTK
FLT1 Receptor Tyrosine Kinase
Proto Oncogene Protein flt
Proto-Oncogene Protein flt
Receptor, FLT VEGF
Tyrosine Kinase, fms-Like
VEGF Receptor flt 1 Protein
VEGF Receptor flt-1 Protein
VEGF Receptor, FLT
VEGFR-1
Vascular Endothelial Growth Factor Receptor 1
fms-Like Tyrosine Kinase



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey