DeCS

Descriptor English:

Receptors, Vascular Endothelial Growth Factor

Descriptor Spanish:

Receptores de Factores de Crecimiento Endotelial Vascular

Spanish from Spain

Descriptor	receptores del factor de crecimiento del endotelio vascular
Entry term(s)	VEGFR receptor VEGF receptor VPF receptor de factor de crecimiento celular endotelial vascular receptor de factor de crecimiento endotelial vascular receptor del factor de crecimiento endotelial receptor del factor de permeabilidad vascular receptores VEGF
Scope note:	Familia de PROTEÍNAS RECEPTORAS TIROSINA CINASAS estrechamente relacionadas que se unen a los factores de crecimiento del endotelio vascular. Comparten un grupo de siete DOMINIOS IG-LIKE extracelulares importantes para la unión a ligandos. Se expresión es abundante en las células endoteliales vasculares y son críticas para el crecimiento fisiológico y patológico, y para el desarrollo y mantenimiento de los vasos sanguíneos y de los vasos linfáticos.

Descriptor Portuguese:

Receptores de Fatores de Crescimento do Endotélio Vascular

Descriptor French:

Récepteurs aux facteurs de croissance endothéliale vasculaire

Entry term(s):

Endothelial Growth Factor Receptor
Receptor, Endothelial Growth Factors
Receptor, Vascular Endothelial Cell Growth Factor
Receptor, Vascular Permeability Factor
Receptors, VEGF
VEGF Receptor
VEGF Receptors
VPF Receptor
Vascular Endothelial Cell Growth Factor Receptor
Vascular Endothelial Growth Factor Receptor
Vascular Permeability Factor Receptor

Tree number(s):

D08.811.913.696.620.682.725.400.950
D12.776.476.568.400.950
D12.776.543.750.630.750
D12.776.543.750.750.400.910

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D040262

Scope note:

A family of closely related RECEPTOR PROTEIN-TYROSINE KINASES that bind vascular endothelial growth factors. They share a cluster of seven extracellular IG-LIKE DOMAINS which are important for ligand binding. They are highly expressed in vascular endothelial cells and are critical for the physiological and pathological growth, development and maintenance of blood and lymphatic vessels.

Annotation:

general; prefer specifics

Allowable Qualifiers:

AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure

Registry Number:

EC 2.7.10.1

Previous Indexing:

Protein-Tyrosine Kinase (1993)
Receptor Protein-Tyrosine Kinases (1994-2002)
Receptors, Growth Factor (1993-2002)
Receptors, Mitogen (1991-1992)

Public MeSH Note:

2003; VASCULAR ENDOTHELIAL CELL GROWTH FACTOR RECEPTOR (now RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR) was indexed under RECEPTORS, GROWTH FACTOR 1993-2002, RECEPTORS PROTEIN-TYROSINE KINASES 1994-2002, PROTEIN-TYROSINE KINASE 1993 & RECEPTORS, MITOGEN 1991-1992; ENDOTHELIAL GROWTH FACTOR RECEPTOR was indexed under RECEPTORS, MITOGEN & RECEPTORS, GROWTH FACTOR 1985-2003

History Note:

2003; use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR (NM) 1991-2002; for ENDOTHELIAL GROWTH FACTOR RECEPTOR use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR (NM) 1985-2003

Concept UI	M0185203
Scope note	A family of closely related RECEPTOR PROTEIN-TYROSINE KINASES that bind vascular endothelial growth factors. They share a cluster of seven extracellular IG-LIKE DOMAINS which are important for ligand binding. They are highly expressed in vascular endothelial cells and are critical for the physiological and pathological growth, development and maintenance of blood and lymphatic vessels.
Preferred term	Receptors, Vascular Endothelial Growth Factor
Entry term(s)	Receptor, Vascular Endothelial Cell Growth Factor Receptor, Vascular Permeability Factor Receptors, VEGF VEGF Receptor VEGF Receptors VPF Receptor Vascular Endothelial Cell Growth Factor Receptor Vascular Endothelial Growth Factor Receptor Vascular Permeability Factor Receptor

Concept UI	M0134921
Preferred term	Endothelial Growth Factor Receptor
Entry term(s)	Receptor, Endothelial Growth Factors

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