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Descriptor English: Poly(A)-Binding Protein I
Descriptor Spanish: Proteína I de Unión a Poli(A)
Descriptor proteína I de unión-poli(A)
Scope note: Proteína de unión a poli(A) que tiene distintas funciones, como la estabilización del ARNm y la protección del ARN de la actividad nucleásica. Aunque se considera que la proteína I de unión a poli(A) es una proteína principal de unión al ARN citoplasmático, también se encuentra en el NÚCLEO CELULAR y puede estar implicada en el transporte de partículas mRNP.
Descriptor Portuguese: Proteína I de Ligação a Poli(A)
Descriptor French: Protéine-1 de liaison au poly(A)
Entry term(s): PAB1 Poly(A) Binding Protein
PABP1 Protein
PABPC1 Protein
Poly(A)-Binding Protein, Cytoplasmic 1
p70 Poly(A) Binding Protein
Tree number(s): D12.776.157.725.452.249
D12.776.664.962.452.249
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D039122
Scope note: A poly(A) binding protein that has a variety of functions such as mRNA stabilization and protection of RNA from nuclease activity. Although poly(A) binding protein I is considered a major cytoplasmic RNA-binding protein it is also found in the CELL NUCLEUS and may be involved in transport of mRNP particles.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: RNA-Binding Proteins (1993-2002)
Public MeSH Note: 2003; P70 POLY(A) BINDING PROTEIN was indexed under RNA-BINDING PROTEINS 1999-2002
History Note: 2003; for P70 POLY(A) BINDING PROTEIN use POLY(A)-BINDING PROTEINS (NM) 1999-2002
DeCS ID: 37407
Unique ID: D039122
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2005/07/21
Poly(A)-Binding Protein I - Preferred
Concept UI M0103429
Scope note A poly(A) binding protein that has a variety of functions such as mRNA stabilization and protection of RNA from nuclease activity. Although poly(A) binding protein I is considered a major cytoplasmic RNA-binding protein it is also found in the CELL NUCLEUS and may be involved in transport of mRNP particles.
Preferred term Poly(A)-Binding Protein I
Entry term(s) PAB1 Poly(A) Binding Protein
PABP1 Protein
PABPC1 Protein
Poly(A)-Binding Protein, Cytoplasmic 1
p70 Poly(A) Binding Protein



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